Hemophilia Pedigree - Father has hemophilia, mother does not. What is the outcome for their kids?
Correct Answer-His daughters would be carriers. This is x-link recessive.
Autosomal:
Dominant: Correct Answer-Autosomal
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Hemophilia Pedigree - Father has hemophilia, mother does not. What is the outcome for their kids?
Correct Answer-His daughters would be carriers. This is x-link recessive.
Autosomal:
Dominant: Correct Answer-Autosomal: males and females equally affected.
Dominant: non-carrier parents
polymerase chain reaction (PCR) Correct Answer-The process of copying DNA in the lab. Uses Template
DNA, Nucleotides (dNTPS), DNA Polymerase, and DNA primers.
3 Steps of PCR Correct Answer-1. Denaturation: DNA is heated to 95C to separate it.
2. Annealing: reaction is cooled to 50C; primers stick to the DNA you want to copy and add DNA
polymerase.
3. Elongation: reaction heated to 70C and DNA polymerase, adding nucleotides building a new DNA
strand.
Base Excision Repair (BER) Correct Answer-How you repair a mutation. BER is used to repair damage to a
base caused by harmful molecules. You remove the base that is damaged and replace it. *BER removes a
single nucleotide*
DNA glycolsylase - sees damaged DNA and removes it.
DNA polymerase-puts the right one back in while DNA ligase seals it.
Mismatch repair (MMR) occurs during: Correct Answer-replication. DNA polymerase proofreads but
sometimes a mismatch pair gets through. MMR removes a large section of the nucleotides from the new
DNA and DNA polymerase tries again. (Ex: C-T instead of C-A)
Mismatch Repair corrects what kind of DNA damage? Correct Answer-When a base is mismatched due
to errors in replication. Such
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