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Week 5: Glucose metabolism disorder(Chamberlain College)
Types of DM
1. Type 1- severe insulin deficiency resulting in reduction or absence of functioning beta cells i
... n
the pancreatic islets of Langerhans. This leads to hyperglycemia due to altered metabolism of
lipids, carbs, and proteins. Initial s/s of hyperglycemia. Subjective findings- polyuria, polydipsia,
nocturnal enuresis and polyphagia with paradoxical weight loss, visual changes and fatigue.
Objective-dehydration(poor skin turgor and dry mucous), wt loss despite normal/increase
appetite, reduction in muscle mass. DKA-fatigue, cramping, abnormal breathing
2. Type 2- Type 2 DM is characterized by the abnormal secretion of insulin, resistance to the action
of insulin in the target tissues, and/or an inadequate response at the level of the insulin receptor.
A patient may, however, present with pruritus, fatigue, neuropathic complaints such as
numbness and tingling, or blurred vision.
3. Prediabetic- fasting glucose consistently elevated above the normal range but less than 100-125.
Impaired glucose tolerance (IGT) state of hyperglycemia where 2 hr post glucose load glycemic
level is 140-199
Diagnostic criteria[Show More]
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