Pathophysiology Practice Test 1
1. Smoking causes lung cancer
a. True
b. False
2. Degenerative changes in cells ultimately lead to cellular necrosis
a. True
b. False
3. Which of the following organ’s cells are the
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Pathophysiology Practice Test 1
1. Smoking causes lung cancer
a. True
b. False
2. Degenerative changes in cells ultimately lead to cellular necrosis
a. True
b. False
3. Which of the following organ’s cells are the most dependent on
oxygen?
a. Liver
b. Kidney
c. Heart
d. Skin
4. Exposure to which of the following could lead to chemical damage to
cells?
a. Antifreeze
b. Antibiotics
c. Heavy metals
d. Alcohol
e. All of the above
f. All but option b
5. Sublethal cellular injury occurs first in what part of the cell?
a. The Endoplasmic Reticulum
b. The Cytoplasm
c. The Golgi Apparatus
d. The Nucleus
6. Hypertrophy and Atrophy are both adaptive cellular responses.
a. True
b. False
7. Liquefactive necrosis is commonly occurs in what organ?
a. The Skin
b. Liver
c. The Heart
d. The Brain
8. When hypertrophied, which of the following organ(s) tend to
accumulate lipids instead of water? (More than one answer may be
correct)
a. Liver
b. Heart
c. Pancreas
d. Kidneys
9. A patient with TB has what look like craters in her lungs; this is an
example of what type of necrosis?
a. Gangrene
b. Caseous
c. Liquefactive
d. Coagulative
10. Also known as postmortem lividity, which postmortem change occurs
due to the pooling of blood due to gravity?
a. Livor Mortis
b. Algor Mortis
c. Rigor Mortis
d. Autophagocytosis
11. Dystrophic calcification can lead to which of the following?
a. Kidney Stone formation
b. Arterial Sclerosis
c. Splinter hemorrhages
d. All of the above
e. a and b
12. Which of the following are considered intrinsic disease pathways?
a. Infection
b. Age
c. Radiation
d. Environmental toxins
13. Which of the following are considered recessive sex-linked disorders
of the x chromosome?
a. Menkes’ disease
b. Hemophilia A
c. Turner’s syndrome
d. G-6-PD
e. All of the above
f. All but c
14. Mutation of a cell is always harmful to the host organism.
a. True
b. False
15. Which of the following have the ability to mutate DNA?
a. Formalin
b. Viruses
c. Antibiotics
d. All of the above
e. only b
16. A congenital disease is the same thing as a genetic disease
a. True
b. False
17. Which of the following results from a hepatic enzyme deficiency that
leads to fatty buildup in the CNS, trouble myelinating nerves and can
cause mental retardation?
a. Tay-Sachs
b. Menkes’ disease
c. PKU
d. Gaucher’s disease
18. Which disease is caused by the lack of a hepatic enzyme and causes
skin pathologies and spleen and liver enlargement?
a. Tay-Sachs
b. Menkes’ disease
c. PKU
d.Gaucher’s disease
19. Which recessive autosomal disorder degrades CNS tissue leading to
motor and neurological disturbance and ultimately early death?
a. Tay-Sachs
b. Menkes’ disease
c. PKU
d. Gaucher’s disease
20. Which of the following are common causes of cellular injury?
a. Oxygen deprivation
b. Nutrient deprivation
c. Ischemia
d. Chemical damage
e. Physical trauma
f. All of the above
g. all but b and c
21. Which of the following are sex-linked diseases?
a. Menkes’ disease
b. Down’s Syndrome
c. Turner’s Syndrome
d. Klinefelter’s Syndrome
22. Down’s Syndrome is associated with which of the following?
a. high incidence of Alzheimer’s disease
b. high incidence of congenital heart valve problems
c. depressed immune system function
d. a third chromosome # 12
e. All of the above
f. all but d
g. all but c and d
23. The Genotype for Klinesfelter’s syndrome is:
a. XXY
b. XXX
c. XYY
d. XO
24. A macule or “sun spot” on the skin is the left over remnant of what
process?
a. Freckling of the skin
b. Dry gangrene
c. Apoptosis
d. Autophagocytosis
e. none of the above
f. only a
25. A first-degree burn involves which layers of the skin?
a. epidermis only
b. epidermis and dermis
c. epidermis, dermis and subcutaneous fat
26. Which of the following is the biggest threat to a burn victim?
a. Stress ulcers and bleeding
b. Loss of skin and potential for infection
c. Increase in fluid volume due to intense thirst
d. Extreme Hypertension
27. What is the most common heat-related issue?
a. Heat Cramps
b. Heat Exhaustion
c. Heat Injury
d. Heat Stroke
28. Malignant Hyperthermia is a condition that involves:
a. Sensitivity to anesthetic shots
b. Sensitivity to anesthetic gases
c. Sensitivity to anesthetic pills
d. Increased muscle metabolism of calcium
e. A genetic link
f. All of the above
g. only b and d
h. only b
29. The textbook definition of hypothermia is a body temperature of:
a. 35 degrees Celsius or less
b. 32 degrees Fahrenheit or less
c. 35 degrees Fahrenheit or less
d. any temperature that slows down enzyme reactions in the body
30. Night-blindness is associated with which vitamin deficiency?
a. Vitamin A
b. Vitamin B6
c. Vitamin E
d. Vitamin D
31. Which Vitamin is given to all newborns to help aid in coagulation?
a. Vitamin A
b. Vitamin B6
c. Vitamin K
d. Vitamin D
32. Which Vitamin is often used to treat peripheral neuropathy
experienced by TB patients from INH therapy?
a. Vitamin B1
b. Vitamin B2
c. Vitamin B6
d. Vitamin B12
33. Which is the correct order of the four d’s of Niacin deficiency (least to
most serious)?
a. Diarrhea, dermatitis, dementia and death
b. Dermatitis, diarrhea, dementia and death
c. Dementia Diarrhea, dermatitis, and death
d. Death, diarrhea, dermatitis and dementia
34. Which of the following is not a fat-soluble vitamin?
a. Vitamin A
b. Vitamin K
c. Vitamin C
d. Vitamin E
35. Toxic levels of Vitamin A can cause which of the following?
a. Cracked skin
b. Fetal defects
c. Spontaneous abortion
d. Impaired of night vision
e. all but d
36. Which two Vitamins are so crucial that our body makes a large
portion of our needed supply on its own?
a. Vitamins B6 and B12
b. Vitamins K and D
c. Vitamins A and E
d. Vitamins K and E
37. Vitamin B1 deficiency:
a. Results in general weakness of the body
b. Is often seen in alcoholics and people with eating disorders
c. Is also called Pellagra
d. Leads to a buildup of pyruvic acid in the body that can interfere with
regular heartbeats
e. all but c
f all but c and d
g. only a
38. Pernicious anemia can result from:
a. Lack of dietary Vitamin B12
b. Lack of intrinsic factor in the stomach
c. The presence of a tapeworm
d. All of the above
e. All but b
39. Inflammation is a natural, useful repair response of the body:
a. True
b. False
40. Inflammation can only occur after the body has become infected:
a. True
b. False
41. The movement of WBC and repair components into an area of
inflammation is called:
a. Hemolytic movement
b. Chemotaxis
c. Adjunct tissue Edema
d. Histamine bombardment
42. A person with one completely burned arm, one completely burned leg
and a completely burned torso would have what approximate % of their
total body burned?
a. 45%
b. 54%
c. 63%
d. 72%
43. Blood pH and plasma potassium levels are:
a. directly proportionate
b. independent of one another
c. inversely proportionate
44. Purulent exudate is also called:
a. Neutrophilic exudate
b. Fibrous exudate
c. Pus
d. Serous exudate
e. Transudate
f. only a
g. only a and c
45. Granulomatous inflammation can be caused as the result of which of
the following?
a. Stroke
b. Bilateral Pitting Edema
C. TB infection
D. Cirrhosis of the liver
46. Which antibodies form the main line of immune defense in the body?
a. IgA
b. IgD
c. IgE
d. IgG
47. Which antibodies are usually the first to respond to newly introduced
antigens?
a. IgA
b. IgD
c.. IgM
d. IgG
48. Which antibody type is produced in overabundance in allergy
suferers?
a. IgA
b. IgE
c.. IgM
d. IgG
e. IgD
49. Anaphylaxis can never occur the first time a person encounters an
antigen because the cells are merely sensitized during this initial contact.
a. True
b. False
c. It depends on how much antigen is present
50. When the nurse suspects a transfusion reaction, what is the first
response?
a. Warm the blood to prevent any cold antibodies from interfering with
transfusion
b. Cool the blood
c. Give Benadryl and blood thinners
d. Discontinue the blood
51. Which autoimmune disease can result in petechiae?
a. SLE
b. Sjogren’s
c. ITP
d. Rheumatoid arthritis
52. Histamine release leads to which of the following?
a. Capillary Dilation
b. Airway Constriction
c. high fever
d. mucus secretion
e. itching of the skin
53. Epinephrine causes which of the following?
a. Fever reduction
b. Bronchi dilation
c. Blood vessel constriction
d. both b and c
e. only b
54. Which autoimmune disease is a disorder of the blood vessels that
results in achy, numb or tingling extremities and is experienced in cold
weather conditions?
a. SLE
b. ITP
c. Reynaud’s disease
d. Sjogren’s
55. Glomerulonephritis results from errant antibodies produced after
infection by which bacteria?
a. T. pallidum
b. staphylococcus
c. streptococcus
d. Cryptococcus
56. Which genetic disorder afects the membrane integrity of red blood
cells, leading to premature cell lysis and hemolytic anemia, often as the
result of exposure to certain drugs?
a. Sjogren’s
b. ITP
c. G-6-PD
d. SLE
57. A virus is considered alive even before introducing itself into a viable
host:
a. True
b. False
58. All viruses are either 100% DNA or 100% RNA but are never mixed
RNA/DNA viruses:
a. True
b. False
59. People who have AIDS most often die of:
a. Kaposi’s sarcoma
b. Pneumonia
c. Candida infection
d. Cancers comorbid with their disease
60. Potential features of SLE include:
a. “Butterfly” rash on face
b. Comorbid rheumatoid arthritis
c. Kidney failure
d. Dry eyes and mucous membranes
e. All of the above
f. b and c only
g. a and c only
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