*NURSING > QUESTIONS & ANSWERS > BIOM 500 Quiz 8 | Questions with Correct Answers (All)

BIOM 500 Quiz 8 | Questions with Correct Answers

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• Question 1 2 out of 2 points Cell cycle-specific anticancer drugs require less frequent dosing/administration in order to prevent tumor resistance. Selected Answer: False Correc ... t Answer: Fals e • Question 2 2 out of 2 points Anticancer drugs are highly distributed into cancer cells because of the increased capacity of these cancer cells for angiogenesis. Selected Answer: False Correct Answer: Fals e • Question 3 0 out of 2 points Hematolymphoid cells express large numbers of MDR1 and ABCG2 making them highly sensitive to chemotherapeutic drugs. Selected Answer: True Correct Answer: Fals e • Question 4 2 out of 2 points Increased tumor heterogenicty increases the likelihood for chemoresistance in tumors. Selected Answer: True Correct Answer: Tru e • Question 5 2 out of 2 points A possible mechanism of tumor resistance to Methotrexate is the increased expression of reduced folate carriers by the tumor cells. Selected Answer: False Correct Answer: Fals e • Question 6 2 out of 2 points Folate deficiency in a cancer patient being treated with 5-Fluorouracil will lead to diminished capacity of this drug to inhibit thymidylatesynthase. Selected Answer: True Correct Answer: Tru e • Question 7 0 out of 2 points Increased expression of the p53 gene in a cancer patient will result in increased rate of apoptosis following chemotheray. Selected Answer: True Correct Answer: Fals e • Question 8 You are evaluating a 55 year old breast cancer patient who has been 2 out of 2 points on Raloxifene and Pertuzumab for the past year, which of these features do you think is least indicative of tumor resistance? Selected Answer: Tumor regression and remission after therapy Correct Answer: Tumor regression and remission after therapy • Question 9 2 out of 2 points In which of these malignancies do you think that chemotherapy has been the least successful in producing tumor remission? Selected Answer: Beast Cancer Correct Answer: Beast Cancer • Question 10 Which of these physiologic mechanisms of drug resistance is overcome by the intrathecal administration of chemotherapeutic agents in leukemia? Selected Answer: Drug Sanctuary sites [Show More]

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