ADVANCED CLINICAL CONCEPTS
• ARDS is an unexpected, catastrophic pulmonary complication
occurring in a person with no previous pulmonary problems.
The mortality rate is high (50%)
• In ARDS, a common laboratory findi
...
ADVANCED CLINICAL CONCEPTS
• ARDS is an unexpected, catastrophic pulmonary complication
occurring in a person with no previous pulmonary problems.
The mortality rate is high (50%)
• In ARDS, a common laboratory finding is lowered PO2.
However, these clients are not very responsive to high
concentrations of oxygen.
• Think about the physiology of the lungs by remembering
PEEP: Positive End Expiratory Pressure is the instillation and
maintenance of small amounts of air into the alveolar sacs to
prevent them from collapsing each time the client exhales.
The amount of pressure can be set with the ventilator and is
usually around 5 to 10 cm of water.
• Suction only when secretions are present.
• Before drawing arterial blood gases from the radial artery,
perform the Allen test to assess collateral circulation. Make
the client’s hand blanch by obliterating both the radial and
ulnar pulses. Then release the pressure over the ulnar artery
only. If flow through the ulnar artery is good, flushing will be
seen immediately. The Allen test is then positive, and the
radial artery can be used for puncture. If the Allen test is
negative, repeat on the other arm. If this test is also negative,
seek another site for arterial puncture. The Allen test ensures
collateral circulation to the hand if thrombosis of the radial
artery should follow the puncture.
• If the client does not have O2 to his/her brain, the rest of the
injuries do not matter because death will occur. However,
they must be removed from any source of imminent danger,
such as a fire.
• PC)2 >45 or PO2 <60 on 50% O2 signifies respiratory failure.
• A child in severe distress should be on 100% O2.
• Early signs of shock are agitation and restlessness resulting
from cerebral hypoxia.
• If cardiogenic shock exists with the presence of pulmonary
edema, i.e., from pump failure, position client to REDUCE
venous return (HIGH FOWLER’s with legs down) in order to
decrease venous return further to the left ventricle.
• Severe shock leads to widespread cellular injury and impairs
the integrity of the capillary membranes. Fluid and osmotic
proteins seep into the extra vascular spaces, further reducing
cardiac output. A vicious cycle of decreased perfusion to ALL
cellular level activities ensues. All organs are damaged, and if
perfusion problems exist, the damage can be permanent.
• All vasopressors/vasodilator drugs are potent and dangerous
and require weaning on and off. Do not change infusion rates
simultaneously.
• A client is brought into the hospital suffering shock symptoms
as a result of a bee sting. What is the first priority?
Maintaining an open airway (the allergic reaction damages the
lining of the airways causing edema). Also, keep the client
warm without constricting clothing; keep legs elevated (not
Trendelenburg because the weight of the lower organs
restricts breathing).
• Epinephrine: 1:1000, 0.2 to 0.5ml subq for mild
• Epinephrine: 1:10,000, or 5ml IV for severe
• Volume expanding fluids are usually given to clients in
shock. However, if the shock is cardiogenic, pulmonary
edema may result.
• Drugs of choice for shock
- Digitalis preparations: Increase the contractility of the heart
muscle
- Vasoconstrictors (Levophed, Dopamine): Generalized
vasonconstriction to provide more available blood to the
heart to help maintain cardiac output.
• A common volume-expanding substance is plasma and
possibly whole blood.
• You are caring for a woman who was in severe automobile
accident several days ago. She has several fractures and
internal injuries. The exploratory laparotomy was successful
in controlling the bleeding. However, today you find that this
client is bleeding from her incision, short of breath, has a
weak thready pulse, has cold and clammy skin, and
hematuria.
- What do you think is wrong with the client, and what would
you expect to do about it?
- These are typical signs and symptoms of DIC crisis. Expect
to administer IV heparin to block the formation of thrombin
(Coumadin does not do this). However, the client described
is already past the coagulation phase and into the
hemorrhagic phase. Her management would be
administration of clotting factors along with palliative
treatment of the symptoms as they arise. (Her prognosis is
poor).
• NCLEX-RN questions on CPR often deal with prioritization
of actions. Question: What actions are required for each of
the following situations?
- A 24-year old motorcycle accident vistim with a ruptured
artery if the leg is pulseless and apneic.
- A 36-year old first time pregnant woman who arrests during
labor.
- A 17-year old with no pulse or respirations who is trapped in
an overturned car, which is starting to catch fire.
- A 40-year old businessman who arrests two days after a
cervical laminectomy.
• WHEN TO SEEK EMERGENCY MEDICAL SERVICE (EMS)
- The American Heart Association recommends that those
with known angina pectoris seek emergency medical care if
chest pain is NOT relieved by three nitroglycerin tablets 5
minutes apart over a 150minute period.
- A person with previously unrecognized coronary disease
experiencing chest pain persisting for 2 minutes or longer
should seek emergency medical treatment.
• It is important for the nurse to stay current with the American
Heart Association’s guidelines for Basic Life Support (BLS)
by being certified every two years as required.
1• If one rescuer is performing CPR, 1 15:2 ratio of compression
to ventilations is performed for 4 cycles, then reassess for
breathing and pulse. If two rescuers are performing CPR, a
15:2 ratio is now recommended for compressions to
ventilations. Perform for 15 cycles with a 100/min
compression rate. When trading off, start with compressions.
• Initiate CPR with BLS guidelines immediately, then move on
to Advanced Cardiac Life Support (ACLS) guidelines.
• When significant arterial acidosis is noted, try to reduce PCO2
by increasing ventilation, which will correct arterial, venous,
and tissue acidosis. Bicarbonate may exacerbate acidosis b
producing CO2. Thus, the ACLS guidelines have
recommended bicarbonate NOT be used unless hyperkalemia
and/or preexisting acidosis is documented.
• Infants/prematures may have problems with the following that
can predispose to arrest: Beware of the “H’s” – hypoxia,
hypoglycemia, hypothermia, increased H+ (metabolic and/or
respiratory acidosis), hypercoagulability (if polycythemia
exists).
• Changes is osmolarity cause shifts in fluid. The osmolarity of
the extracellular fluid (ECF) is almost entriely due to sodium.
The osmolarity of intracellular fluid (ICF) is related to many
particles, with potassium being the primary electrolyte. The
pressures in the ECF and the ICF are almost identical. If
either ECF or ICF change in concentration, fluid shifts from
the area of lesser concentration to the area of greater
concentration.
• Dextrose 10% is a hypertonic solution and should be
administered IV.
• Normal saline is an isotonic solution and is used for irrigations,
such as bladder irrigations or IV flush lines with intermittent IV
medication.
• Use only isotonic (neutral) solutions in irrigations, infusions,
etc., unless the specific aim is to shift fluid into intracellular or
extracellular spaces.
• Potassium imbalances are potentially life-threatening, must be
corrected immediately. A low magnesium often accompanies
a low K+, especially with the use of diuretics.
• Fluid Volume Deficit: Dehydration
- Elevated BUN: The BUN measures the amount of urea
nitrogen in the blood. Urea is formed in the liver as the end
product of protein metabolism. The BUN is directly related to
the metabolic function of the liver and the excretory function of
the kidneys.
- Creatinine, as with BUN, is excreted entirely by the kidneys
and is therefore directly proportional to renal excretory
function. However, unlike BUN, the creatinine level is affected
very little by dehydration, malnutrition, or hepatic function.
The daily production of creatinine depends on muscle mass,
which fluctuates very little. Therefore, it is a better test of
renal function than is the BUN. Creatinine is generally used in
conjunction with the BUN test and they normally are in a 1:20
ratio.
- Serum osmolality measures the concentration of particles in a
solution. It refers to the fact that the same amount of solute is
present, but the amount of solvent (fluid) is decreased.
Therefore, the blood can be considered “more
concentrated.”
- Urine osmolality and specific gravity increase.
• Check the IV tubing container to determine the drip factor
because drip factors vary. The most common drip factors
are 10, 12, 15, and 60 drops per milliliter. A microdrip is 60
drops per milliliter
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