NURS 6521 week 6 Q&A, With Answered Solutions guide, 2022.-can be defined as the study of drugs that later processes controlled by the nerovus sytem - neuropharmacology
two basic steps of of neuropharmacologic drugs..
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NURS 6521 week 6 Q&A, With Answered Solutions guide, 2022.-can be defined as the study of drugs that later processes controlled by the nerovus sytem - neuropharmacology
two basic steps of of neuropharmacologic drugs.... - axonal conductionand synaptic conduciton
two influence a process under neuronal control, a drug can alter one of two basic neuronal activities...
1)
2) - 1) axonal conduction
2) synaptic transmission
is axonal coonduction very selective? - no
drugs that alter synaptic transmission can produce effects that are _______( highly or minimally?) selective? - highly
the ability of a neuron to influence the behavior of another cell depends untilamtely on what? - the ability of the neuron to alter receptor activity on the target cell
T or F. the effect of a drug on a neuronally regulated process is dependent on the ability of that drug to directly or indirectly influence receptor activity on target cells. - TRUE very important
for synaptic transmission to take Place alce, molecules of transmitter must be present in the ________ _______? - nerve terminal
what is the first step of transmission for neuro drugs? - transmitter synthesis
what is the second step of transmitter storage? - transmitter storage
what is step 3 of synaptic transmission? - transmitter release
transmitter release is triggered by the arrival of an ______ _____- - action potential
after release, transmitter molecules _______ across the synaptic gap and then undergo reversible binding to receptors ton the postsynaptic cell - diffuse
the 5th step in transmitter release is when the transmission is terminated by dissociation of transmitter from its receptor, followed by removal of a free transmitter from the synaptic gap -
transmitter can be removed fomr the synaptic gap by three processes
1
2
3 - 1 reuptake
2 enzymatic degradation
3 diffusion
in synapses where the transmitter is cleared by enzymatic degradation, the synapse contains large quantities of transmitter-inactivating _______- - enzymes
all neuropharmacologic agents, produce their effects by directly or indirectly altering __________ _________. - receptor activity
T or F receptor activtoin can make a process only go faster? - FALSE it can mek it go faster or slower
there are 3 different effects that drugs are known to have on. transmitter synthesis - 1 increase transmitter synthesis
2 decrease transmitter synthesis
3 cause the synthesis to transmitter molecules that are more effective than the natural transmitter itself
a drug that increases transmitter synthesis will cause receptor activation to ( INCREASE OR DECReASE)? - increase
release of "super" transmitters will cause recepto ractivaiton to ________ - increase
drugs that interefere with transmitter storagfe will cause the receptor activation to ( INCREASE OR DECREASE)? - decrease
drugs either promote or inhibit transmitter release, amphetamines are examples of drugs that represent - promoting transmitter relsease
drugs that omhibit relsease will ______ receptor activation - reduce
drugs that directly activate receptors are called ______ - agonists
drugs that prevent receptor activation are called ______ - antagonists
do morphine, insulin and epinephrine bind directly to the receptor and cause activation? - yes
drugs like naloxone, antihistamines and metoprolol bind directly to receptors and prevent activation, True or false? - true
Benzodiazepines are an excellent example of a drug that binds to receptors and ________ the actions of a natural transmitter. - enhance
T or F. Drugs can interfere with the termination of transmitter action by two mechanisms:
1 blockade of transmitter reuptake
2inhibtion of transmitter degradation - true
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