spring 2022: biomed exam #4 practice
questions – COMPLETE SOLUTION
State true or false: Warfarin is an antagonist of Vitamin K.
A. True
B. False - ✔✔A
Regarding Vitamin K and its role, which of the following stateme
...
spring 2022: biomed exam #4 practice
questions – COMPLETE SOLUTION
State true or false: Warfarin is an antagonist of Vitamin K.
A. True
B. False - ✔✔A
Regarding Vitamin K and its role, which of the following statements are correct?
A. Vitamin K epoxide reducatase complex subunit 1 converts oxidized form of vitamin K to reduced
form.
B. Vitamin K is essential for the maturation of certain coagulation factors
C. Vitamin K is a cofactor for the enzyme g-glutamyl carboxylase
D. Warfarin inhibits VKORC1
E. All of the above - ✔✔E
Vitamin K is important for the maturation of which of the following coagulation factors?
A. Factor II
B. Factor VII
C. Factor IX
D. Factor IX
E. All of the above - ✔✔E
State true or false. ADP can cause platelet aggregation whereas Adenosine diphosphatase can prevent
platelet aggregation by degrading ADP.
A. True
B. False - ✔✔A
List hereditary reasons for the development of VTE - ✔✔Mutations in factor II and Factor V
Deficiency in protein C and deficiency in anti-thrombin
High levels of factor VIII
What is the co-factor for gamma glutamyl carboxylase enzyme?
A. Vitamin A
B. Vitamin D
C. Vitamin K
D. Vitamin E - ✔✔C
Which of the following CYPs are involved in the metabolism of Warfarin?
A. CYP2C9
B. CYP1A
C. CYP3A4
D. All of the above - ✔✔D
Black box warning in prescription drugs is_______
A. It is a type of alert notification that appears on the package insert for certain prescription drugs which
notifies patients on the risk associated with taking the drugs due to gene polymorphisms.
B. Alert notification to take the drug after the food in the morning and night
C. Alert notification to indicate that it is only to be given people who are above 20 years old.
D. Alert notification to indicate that it is used in treating animal diseases. - ✔✔A
Clinically relevant CYP enzyme involved in the metabolism of warfarin is________
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