Georgette's LMR PMHNP Certification Exam Review, 2022-What drugs should be avoided with Kava Kava?
- Alprazolam
CNS depressants (e.g., phenobarbital, zolpidem)
Cultural Formulation Interview perform what 3 function
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Georgette's LMR PMHNP Certification Exam Review, 2022-What drugs should be avoided with Kava Kava?
- Alprazolam
CNS depressants (e.g., phenobarbital, zolpidem)
Cultural Formulation Interview perform what 3 functions? - Clarify meaning of illness
Empower the patient
Validate symptoms within cultural context
What does a cultural formulation interview do? - cultural assessment
What is the normal range for TSH? - 0.5 - 5.0 mu/L
What are lab values in Hyperthyroidism - Decreased TSH
Increased T4 and T3
What are labs in Hypothyroidism? - Increased TSH
Decreased T4 and T3
What are 5 primary symptoms of Hyperthyroidism? - Heat intolerance
Agitation, Anxiety, Irritability
Tachycardia
Mood swings
Weight loss
What are 4 primary symptoms of Hypothyroidism? - Cold intolerance
Lethargy
Weight gain
Decreased libido
Hypothyroidism mimics symptoms of what psychiatric disorder? - Depression
Hyperthyroidism mimics symptoms of what psychiatric disorder? - Mania
Valproic acid produces what teratogenic effect? - Spina bifida (neural tube defect)
What is the primary organ where valproic acid is toxic? - Liver (hepatoxicity)
What are 4 signs of hepatoxicity? - Abdominal pain in the URQ
Reddish-brown urine
Yellowing of the skin and sclera
Fatigue
Abdominal pain in the URQ, Reddish-brown urine, Yellowing of the skin and sclera, and Fatigue are signs of - Hepatoxicity
What is the therapeutic range for valproic acid? - 50-125 mcg/ml
What is a toxic level of valproic acid? - >150 mcg/ml
What are 4 signs of valproic acid toxicity? - Disorientation
Lethargy
Respiratory depression
Nausea/vomiting
Disorientation, Lethargy, Respiratory depression, and Nausea/vomiting are symptoms of toxicity with what drug? - Valproic acid
With suspected toxicity with valproic acid, what labs should be drawn? - DC drug
Check drug level
Obtain LFTs
Obtain ammonia level
What is the major side effect with Kava Kava? - Liver damage
What herbal supplement is sued for anxiety, stress, and insomnia? - Kava Kava
What are 5 symptoms of Stephen's Johnson Syndrome? - Fever
Body aches
Severe red rash
Peeling skin
Facial and tongue swelling
Severe red rash, Fever, Body aches, Peeling skin, and Facial and tongue swelling are symptoms of - Stephen's Johnson Syndrome
Which mood stabilizer causes the least weight gain? - Lamotrigine (Lamictal)
Which 3 SGAs cause the least weight gain? - Lurasidone (Latuda)
Aripiprazole (Abilify)
Ziprasidone (Geodon)
Which SGA is the least sedating? - Aripiprazole (Abilify)
What are 3 hallmark symptoms of delirium? - Acute disturbance of LOC
impaired cognition
inattention
Acute disturbance of LOC, cognition, and inattention are hallmark symptoms of - Delirium
How are agitation and psychotic symptoms treated in delirium? - Low dose Haldol
What 4 drugs can cause mania? - Steroids
Disulfiram (Antabuse)
Isoniazid (INH)
Antidepressants (in BPD)
Steroids, Disulfiram (Antabuse), and Isoniazid (INH) can induce - Mania
What 6 drugs can induce depression? - Steroids
Beta blockers
Interferon, Isotretinoin (Accutane)
Retroviral drugs, Antineoplastic drugs
Benzodiazepines
Progesterone
Steroids can induce what 3 psychiatric states? - Mania
Depression
Psychosis
What medication to treat acne cause cause birth defects? - Isotretinoin (Accutane)
What is the therapeutic range for lithium? - 0.6-1.2 mEq/L
What medication has a neuroprotective effect for bipolar disorder? - Lithium
What is the gold standard for treating manic episodes - Lithium
What mood stabilizer has anti-suicidal effects? - Lithium
What 5 labs should be drawn with lithium? - Thyroid panel (TSH)
Serum creatinine
BUN
Urinalysis
HCG
What is a normal SCr range? - 0.6-1.2 mg/dL
What is the normal range for BUN? - 10-20 mg/dL
When should you suspect kidney disease with a urinalysis? - 4+ protein
4+ protein in the kidney suggests - Kidney disease
What are 7 side effects of lithium? - Hypothyroidism
Fine hand tremors
Maculopapular rash
GI upset (N/V/D, cramps, anorexia)
Polyuria, polydipsia, diabetes insipidus
T-wave inversions
Leucocytosis
What are 7 signs of lithium toxicity? - Severe nausea, vomiting, diarrhea
Confusion
Drowsiness
Muscle weakness
Heart palpitations
Coarse hand tremor
Unsteadiness while standing or walking
Which 3 drugs can increase lithium levels by decreasing renal clearance? - NSAIDs (ibuprofen, indomethacin)
Thiazides
ACEI
What is a toxic level of lithium? - 1.5 mEq/L or higher
At what level do you monitor lithium closely
(but not discontinue)? - 1.3 mEq/L or higher
With suspected lithium toxicity, what do you do first? - Lithium level (not VS)
What is the appropriate action if lithium level is 1.5 mEq/L? - DC lithium
Check lithium level
What 2 conditions can increase lithium levels? - Dehydration
Hyponatremia
What birth defect can lithium cause? - Ebstein anomaly (congenital heart defect)
What 3 neurotransmitters are associated with ADHD? - DNS
What 3 parts of the brain are affected with ADHD? - Frontal cortex
Basal ganglia
Reticular Activating System
The Frontal cortex, Basal ganglia, Reticular Activating System are associated with which psychiatric disorder? - ADHD
Inattentive Type ADHD demonstrates abnormalities in which part of the brain? - Prefrontal cortex
What should be done before placing a patient on stimulants for ADHD (priority)? - Cardiac history
Excessive worry, apprehension, or anxiety about events or activities that occurs more days than not for a period of at least 6 months is - GAD
If a patient is receiving Haldol 5 mg PO bid, how much Haldol Decanoate should they receive? - 20 x 10 mg = 200 mg (q month)
What is the formula for converting oral Haldol to depot form? - 20 x daily dose
What does thought process assess? - thoughts and ideas
The way a patient organizes his thoughts and ideas is called - Thought process
A normal thought process is described as - Logical
Linear
Coherent
Goal-oriented
Moving from thought to thought and never getting to the point is called - Tangentiality ("goes on tangent")
Providing unnecessary detail but eventually getting to the point is called - Circumstantiality ("goes in circles")
Themes that occupy a patient's thoughts and perceptual disturbances is called - Thought content
Thought content includes 3 items - Suicidal ideation
Homicidal ideation
Hallucinations/Delusions
Asking a patient to count backward from 100 by seven (serial 7s) measures 3 processes - Concentration
Attention
Calculation
Asking the year, season, date, month, and location measures - Orientation
Asking a patient to repeat "bed, bad, ball" measures - Registration (ability to learn new material)
Asking a patient to repeat objects 5 minutes later measures - Recall (memory)
Asking the patient who is the president of the US or governor of state is measuring - Fund of Knowledge
What is a simple test that can be administered in a minute or two to measure possible dementia? - Clock Drawing Test
Impairments in the clock drawing test (CDT) can be associated with damage to - Right parietal lobe (right hemisphere)
Hyperactivity of dopamine in the mesolimbic pathway modulates - positive psychotic symptoms
Decreased dopamine in the mesocortical pathway (dorsolateral prefrontal cortex) leads to what 2 symptoms? - Negative symptoms
Depressive symptoms
The nigrostriatal pathway modulates - motor movements
Dopamine has what type of relationship with acetycholine - Inverse
Dopamine blockage in the nigrostriatal pathway leads to what 4 side effects? - Acute dystonia
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