Central Dogma of Genetics Assignment
OVERVIEW
This worksheet complements the Central Dogma and Genetic Medicine Click & Learn from HHMI
BioInteractive. This worksheet comes directly from HHMI BioInteractive.
PROCEDUR
...
Central Dogma of Genetics Assignment
OVERVIEW
This worksheet complements the Central Dogma and Genetic Medicine Click & Learn from HHMI
BioInteractive. This worksheet comes directly from HHMI BioInteractive.
PROCEDURE
As you proceed through the Click & Learn, follow the instructions below and answer the questions in the
spaces provided.
1. Let’s review! The central dogma of molecular biology refers to the process of gene expression. Write
the definition of gene expression in your own words.
A surfacing of a phenotype of a characteristic or effect assigned to a certain gene.
2. Click on the “Central Dogma” menu tab at the top of the screen.
The table below outlines the steps in eukaryotic gene expression. Click on each tab in the tutorial
and briefly summarize each step below. There are little arrows next to each molecule involved. Click
on these to get more information on each molecule.
Gene expression steps Molecules involved
What molecules and proteins are
involved in this step?
Summary
What happens during this step?
Transcription RNA polymerase, DNA, RNA,
Exon, and Intron.
RNA Polymerase converts
information from a section of
the DNA into a complementary
sequence with the tRNA.
RNA Splicing Spliceosome, Inron, and Exon.
The spliceosome cuts up
introns and splices together
exons to create mRNA.
mRNA Transport mRNA
The mRNA is sent out the
nucleus and into the
cytoplasm.
Translation mRNA, tRNA, Ribosome, and
Polypeptide.
Amino acids are put together
in a chain by the ribosome
once it reads the code from
the tRNA that it received from
the mRNA.
Protein Processing Polypeptide
When the chain is complete
the polypeptide will fold into a
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