Pharmacology > EXAM > PHARMACOLOGY, TOXICOLOGY, PHARMACOKINETICS (All)

PHARMACOLOGY, TOXICOLOGY, PHARMACOKINETICS

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1. Two dose-response curve response plotted on the same graph showed sigmoid curves having the same slope and height. T curve is located to the right of the A curve. Which of the following statements ... is/are correct regarding curves A an: I. A is more effective than B II. A is more potent than B III. A and B have the same ceiling dose IV. B is the graph produced when A is given with its competitive antagonist V. B is the graph produced when A is given with its non-competitive antagonist a. Only I and III are correct b. Only II, III and IV are correct c. Only II and IV are correct d. Only III and V are correct e. Only V is correct 2. Two dose-response curve plotted on the same graph showed sigmoid curves A and B, where A is at the left of the graph with the height greater than B. Which of the following statements is/are correct regarding curves A and B? I. A and B has equal efficacy II. A and B have equal potency III. B is a partial agonist of A IV. B is the graph produced when A is given with its competitive antagonist V. B is the graph produced when A is given with its non-competitive antagonist a. Only I and III are correct b. Only II, III and IV are correct c. Only II and IV are correct d. Only III and V are correct e. Only V is correct 3. The cumulative number of subjects who display a certain rersponse or effect to a drug is plotted on a graph as shown below. The graph on the left represents beneficial effect while the graph on the right represents toxic effect, what is the therapeutic index of the drug? a.0.5 b. 1.5 c. 2.5 d.4.0 e. 5.0 4. An administration of one drug leads to a shift in the log dose-response curve of another drug to the left a range in the maximal efficacy, thi [Show More]

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