Biochem C785 - WGU - Module 5 - All
Questions
What vitamin does not travel through the bloodstream in the form of a lipid micelle? Correct Answer:
Vitamin C
Which lipid has a 4-ring structure? Correct Answer: Sterol
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Biochem C785 - WGU - Module 5 - All
Questions
What vitamin does not travel through the bloodstream in the form of a lipid micelle? Correct Answer:
Vitamin C
Which lipid has a 4-ring structure? Correct Answer: Sterol
Which of the following situations is MOST likely to increase the rate of beta oxidation? Correct
Answer: fasting
A patient who is on a no-fat diet is at particular risk of deficiency in: Correct Answer: Vitamin A
During starvation, triglycerides can help supply some of the body's glucose needs. Which breakdown
product of triglycerides can be used to make glucose? Correct Answer: glycerol
CH3(CH2)6CH=CH(CH2)2COOH Correct Answer: liquid at the lowest temperature
Describe the steps involved in fatty acid synthesis Correct Answer: Acetyl-CoA is transported to the
cytoplasm - Biotin transfers a carboxylate group to acetyl-CoA - the malonyl group is transferred to a
carrier protein - malonyl ACP combines with acetyl-CoA, - malonyl-CoA is added repeatedly to the
growing fatty acid
What fatty acid will produce 8 Acetyl CoA molecules after it is completely metabolized via beta
oxidation? Correct Answer: CH3(CH2)4CH=CH(CH2)4CH=CH(CH2)8COOH
Which set of molecules are produced by the beta oxidation of fatty acids? Correct Answer: Acetyl
CoA, NADH, FADH2
Gastric bypass surgery results in an increase in the production of GLP-1, a peptide that promotes
insulin secretion. This is thought to be associated with the tendency for these patients' type II
diabetes to resolve after the surgery. If a gastric bypass patient has a mutation in GLP-1 that impairs
its function, what is to be expected? Correct Answer: The patient would have reduced insulin
secretion compared to patients with normal GLP-1, and this reduction results in increased fatty acid
oxidation
Through mandatory state testing, a 2-day-old newborn is found to have a medium chain acyl-COA
dehydrogenase deficiency (MCADD). This enzyme deficiency interferes with the baby's ability to
break down medium chain fatty acids via beta oxidation. Her parents need to be given specific
instructions on what the baby can ingest. What is correct? Correct Answer: She will not be able to
utilize adipose tissue for ATP production as effectively as a baby without the disorder
Which of the following contributes to the development of ketoacidosis in a diabetic patient Correct
Answer: A reduction in citric acid cycle intermediates, which decreases the amount of oxaloacetate
that acetyle-CoA can combine with to enter the citric acid cycle
What describes a fatty acid? Correct Answer: C16H3202
Unsaturated fatty acids can have different arrangements of hydrogen atoms at the double bond
depending on whether the bonds are cis- or trans- configuration. A consequence of this : Correct
Answer: fatty acids with cis-configuration double bonds do not pack together well which lowers their
melting point
What best describes fatty acid hydrogenation? Correct Answer: Hydrogenation converts some
unsaturated fatty acids into saturated fatty acids
Phospholipids have parts that are hydrophobic (non-polar, not soluable in water) and a part that is
hydrophilic (polar; water-soluable). What term do we use to describe a molecule that is both polar and
non-polar? Correct Answer: amphipathic
Which compounds make up the greatest reserves of energy in our bodies? Correct Answer:
triglydercides
Acetyl-CoA is a central to metabolism. Carbohydrates, proteins, and fats can all produce Acetyl-CoA,
though they use different pathways to make it. Correct Answer: True
Beta oxidation of a C14 fatty acid will make 6 acetyl-CoA units after 7 rounds of beta-oxidation
Correct Answer: True
Mammals and plants have the ability to synthesize their fatty acids. Which one of the following
molecules is the precursor to building fatty acids? Correct Answer: Acetyl-CoA
Acetyl-CoA, a central molecule in metabolism, is produced in the mitochondrial matrix. However, it is
used for the synthesis of fatty acids in the cytosol. The transport of the acetyl-CoA from the matrix to
the cytosol occurs by the conversion of acetyl-CoA to Correct Answer: citrate
The inability to tolerate long-chain fatty acids in the diet could stem from a defect in Correct Answer:
beta-oxidation of long-chain fatty acids
Ketoacidosis is a dangerous outcome of uncontrolled diabetes. It is a result of the buildup of ketone
bodies. What is the primary metabolic fuel that results in the build-up of the ketone bodies? Correct
Answer: fatty acids
Fatty acid synthesis occurs in the cytosol, so its building block molecule acetyl-CoA must be
transported out of the mitochondria and into the cytosol using the citrate transport system. The acetylCoA is then combined with carbon dioxide with the help of the coenzyme molecule biotin in order to
form malonyl-CoA in the first committed step of fatty acid synthesis. Correct Answer: True
Which molecule is considered a lipid? Correct Answer: 1. sterol
2. fat
3. wax
The acid portion of a fatty acid corresponds to which one of the following groups/molecules? Correct
Answer: COOH is a carboxylic acid group. A fatty acid consists of a hydrocarbon chain bound to the
carbon atom of the COOH. Answer: COOH
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