ALAT chapter 2 questions and answers 2022

What is NOT a component of an animal care and use program described in the guide? A. Genotyping procedures B. Euthanasia C. Personal qualifications D. Animal environment and housing Genotyping procedures ...

What is NOT a component of an animal care and use program described in the guide? A. Genotyping procedures B. Euthanasia C. Personal qualifications D. Animal environment and housing Genotyping procedures What is NOT a requirement of the AWA/AWR a researcher must comply with, if they house covered species? A. Provide dogs with exercise B. Appoint an unaffiliated member to the IACUC C. Meet or exceed sanitization standards for both cages and facility D. Submit an annual report including the number of covered species used B. Appoint an unaffiliated member to the IACUC What types of euthanasia methods are listed in the AVMA guidelines for euthanasia of animals? Acceptable, conditionally acceptable, and unacceptable methods What is stated as a requirement for compliance with the US principles for the utilization and c are of vertebrate animals used in testing research and training? Animals that suffer unrelieved pain and distress should be painlessly killed at the end of the procedure Transportation, use and care of animals should be in accordance with the Animal Welfare Act Procedures that cause more than momentary or slight pain must be performed with appropriate sedation, analgesia, and anesthesia True of false: the PHS policy covers all live vertebrates used or intended for use in research, training, experimental purposes, and biological testing. True According to the animal welfare regulations, to which official does the IACUC report? The institute official (IO) or the Chief Executive Officer (CEO) Which document on animal research is reviewed and approved by the Institutional Animal Care and Use committee? Animal use protocol Which agency is responsible for enforcing the Public Health Service Policy on Humane Care and Use of Laboratory Animals (PHS Policy)? Office of laboratory animal welfare What federal agency is responsible for enforcing and administering the Animal Welfare Regulations? Animal and plant health inspection service Which of the following species is covered by the animal welfare act? A. Zebra fish B. Mice C. Hamsters D. Birds bred specifically for research C. Hamsters Why is the term for the field of study concerned with the philosophical issues rises by some medical procedures and treatments? Bioethics Which organization accredits laboratory animal facilities that demonstrate that they are meeting the standby outlines in the guide and all federal and local regulations? AAALAC international Using the minimum number of animals that will serve a useful purpose, yet yeild statistically sound data and produce scientific benefit demonstrates which principle? reduction What government agency is in charge of preparing standards and enforcing the Animal Welfare Act? USDA Why national nonprofit organization offers certification for Laboratory Animal Technicians? AALAS Identify the members of the research team Principal investigator Laboratory animal technicians Laboratory animal veterinarians Commercial animals supplier What is the name of the committee made up of scientists and nonscientists that reviews animal use protocols, inspects they animal facility, and monitors experimental procedures in which animals are used? IACUC What is the name of the voluntary accreditation organization that inspects and accredits animal care programs? AAALAC, international What do the 3Rs stand for in regards to animal experimentation? Replacement, refinement, reduction Which organization published the 2000 panel on euthanasia, which is considered the standard to which all methods or euthanasia proposed in animal research protocols are judged? AVMA Which organization represents the interests of the public and the scientific community in areas of legislation and regulations on the use of laboratory animals? NABR Identify the 4 members that should make up the Institutional Animal Carr and Use committee. Veterinarian with lab animal medicine experience Scientist with animal use experience Nonscientist Outside member not affiliated with the institution What document is used by AAALAC, international as the "gold standard" to evaluate an accredited laboratory animal care and use program? The guide for the care and use of laboratory animals Guide for the Care and Use of Laboratory Animals Primary source of the standards and guidelines for laboratory animal care and use in the United States Animal use protocol A document written by the Principal Investigator and approved by the IACUC, that describes and justifies the use of animals for a project PHS Policy Federal mandate that covers all live vertebrates used or intended for use in research, research training, experimentation, biological testing, or for related purposes Good Laboratory Practices Regulations developed by the food and drug administration (FDA) and the environment protection agency (epa) to validate and document the processes of safety testing Standard Operating Procedures (SOPs) Written instructions approved by management and used to perform a routine activity According to the animal welfare act, list the three types of members who must sit on the institutional animal care and use Chair Vet Non-affiliated member List five components of an animal care and use program for which the guide describes the standard Personal qualifications and training Occupational health and safety Veterinary care Animal environment Animal procurement and transportation Surgical and postsurgical care Alleviation of pain and distress Euthanasia Physical plant design and construction Which animals used in laboratory animal research would be covered by the animal welfare act Guinea pigs rabbits hamsters ferrets wild mice horses gerbils goats sheep What are the requirements in the animals welfare act and the animals welfare regulations if covered species are used Register with USDA Appoint an IACUC Provide training for all animal users Maintain animals records Provide adequate housing Meet sanitization Etc. The appropriate use of analgesics in postsurgical animals would apply to which of the 3Rs principles ? Refinement List two alternatives to using animals models for research Cell culture Mathematical models Beyond food, water, shelter, and healthcare requirements, to comply with the AWA, what must be provided to dogs in a laboratory animal research facility? Exercise