PATHOPHYSIOLOGY
THE BIOLOGIC BASIS FOR DISEASE IN ADULTS AND CHILDREN
8th Edition
Kathryn L. McCance, Sue E. Huether
2
Contents
Chapter 01: Cellular Biology..........................................................
...
PATHOPHYSIOLOGY
THE BIOLOGIC BASIS FOR DISEASE IN ADULTS AND CHILDREN
8th Edition
Kathryn L. McCance, Sue E. Huether
2
Contents
Chapter 01: Cellular Biology..........................................................................................................................4
Chapter 02: Altered Cellular and Tissue Biology: Environmental Agents...................................................18
Chapter 03: The Cellular Environment: Fluids and Electrolytes, Acids and Bases......................................31
Chapter 04: Genes and Genetic Diseases...................................................................................................44
Chapter 05: Genes, Environment-Lifestyle, and Common Diseases...........................................................55
Chapter 06: Epigenetics and Disease..........................................................................................................63
Chapter 07: Innate Immunity: Inflammation and Wound Healing.............................................................68
Chapter 08: Adaptive Immunity..................................................................................................................83
Chapter 09: Alterations in Immunity and Inflammation.............................................................................95
Chapter 10: Infection ................................................................................................................................108
Chapter 11: Stress and Disease.................................................................................................................117
Chapter 12: Cancer Biology.......................................................................................................................124
Chapter 13: Cancer Epidemiology.............................................................................................................137
Chapter 14: Cancer in Children.................................................................................................................143
Chapter 15: Structure and Function of the Neurologic System................................................................148
Chapter 16: Pain, Temperature Regulation, Sleep, and Sensory Function...............................................159
Chapter 17: Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function...............174
Chapter 18: Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction
..................................................................................................................................................................188
Chapter 19: Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders ...........................199
Chapter 20: Alterations of Neurologic Function in Children.....................................................................206
Chapter 21: Mechanisms of Hormonal Regulation...................................................................................213
Chapter 22: Alterations of Hormonal Regulation .....................................................................................222
Chapter 23: Obesity and Disorders of Nutrition.......................................................................................234
Chapter 24: Structure and Function of the Reproductive Systems..........................................................239
Chapter 25: Alterations of the Female Reproductive System ..................................................................249
Chapter 26: Alterations of the Male Reproductive System......................................................................259
Chapter 27: Sexually Transmitted Infections............................................................................................265
Chapter 28: Structure and Function of the Hematologic System.............................................................273
Chapter 29: Alterations of Erythrocytes, Platelets, and Hemostatic Function.........................................283
3
Chapter 30: Alterations of Leukocyte and Lymphoid Function ................................................................293
Chapter 31: Alterations of Hematologic Function in Children..................................................................300
Chapter 32: Structure and Function of the Cardiovascular and Lymphatic Systems ...............................311
Chapter 33: Alterations of Cardiovascular Function.................................................................................324
Chapter 34: Alterations of Cardiovascular Function in Children ..............................................................338
Chapter 35: Structure and Function of the Pulmonary System................................................................346
Chapter 36: Alterations of Pulmonary Function.......................................................................................356
Chapter 37: Alterations of Pulmonary Function in Children.....................................................................373
Chapter 38: Structure and Function of the Renal and Urologic Systems .................................................381
Chapter 39: Alterations of Renal and Urinary Tract Function ..................................................................391
Chapter 40: Alterations of Renal and Urinary Tract Function in Children................................................401
Chapter 41: Structure and Function of the Digestive System...................................................................409
Chapter 42: Alterations of Digestive Function..........................................................................................421
Chapter 43: Alterations of Digestive Function in Children .......................................................................432
Chapter 44: Structure and Function of the Musculoskeletal System.......................................................441
Chapter 45: Alterations of Musculoskeletal Function ..............................................................................453
Chapter 46: Alterations of Musculoskeletal Function in Children............................................................466
Chapter 47: Structure, Function, and Disorders of the Integument.........................................................475
Chapter 48: Alterations of the Integument in Children............................................................................486
Chapter 49: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults....................................494
Chapter 50: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children ................................502
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