Tissue resident sentinel cells include (3 types) Correct Answer Dendritic cells, macrophages, and mast cells
Circulating leukocytes involved in innate response (2 types) Correct Answer Monocytes and neutrophils
Pha
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Tissue resident sentinel cells include (3 types) Correct Answer Dendritic cells, macrophages, and mast cells
Circulating leukocytes involved in innate response (2 types) Correct Answer Monocytes and neutrophils
Phagocytic immune cells (2 types) Correct Answer Macrophages and neutrophils
Difference between macrophages and neutrophils? Correct Answer Neutrophils are short lived and will undergo apoptosis after eating a microbe; macrophages are longer-lived and will eat apoptotic cells and waste
General cytokine role in innate immune response (and what cells release them?) Correct Answer Released by Dendritic cells, macrophages, and mast cells. Pro-inflammatory molecules that interact with blood vessel endothelium to recruit circulating leukocytes, fluid, and proteins into tissue
Which tissue-resident sentinel cell will release histamine upon activation? Correct Answer Mast cell
Cytokines promote up-regulation of what kind of molecule within blood vessel walls? Correct Answer Adhesion molecules
E-Selectin Correct Answer An adhesion molecule that helps to slow down circulating leukocytes in innate immune response (low-affinity interaction)
E-Selectin Ligand Correct Answer A ligand expressed by circulating leukocytes that helps them stick to blood vessel endothelium in innate immune response
ICAM-1 Correct Answer An adhesion molecule that helps circulating leukocytes bind to blood vessel endothelium in innate immune response (high-affinity interaction)
Integrins (and the name of a specific one) Correct Answer A class of adhesion molecules expressed on circulating leukocytes; LFA-1 binds to ICAM-1 in a high affinity interaction during the innate inflammatory response
Stable Arrest Correct Answer When a circulating leukocyte comes to a stop within the endothelium thanks to adhesion molecule interactions and can enter the tissue
Pus Correct Answer Comprised of fluid and apoptotic cells/waste as a result of an inflammatory response (DNA, dead bacteria, apoptotic neutrophils)
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