BioChemistry > QUESTIONS & ANSWERS > USMLE STEP 1 FIRST AID - BIOCHEMISTRY NOTES|QUESTIONS WITH CORRECTS (All)
USMLE STEP 1 FIRST AID - BIOCHEMISTRY NOTES|QUESTIONS WITH CORRECTS
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Heterochromatin Correct Answer Condensed, transcriptionally inactive ("H heterochromatin = H highly C condensed.")
Euchromatin Correct Answer Less condensed, transcriptionally active (Eu = true, "truly transcribed")
Purines Correct Answer A, G 2 Rings ("PUR e A s G old = purine") 
Pyrimidines Correct Answer C, T, U 1 ring ("CUT the PY (pie): PYrimidines") 
Functional groups of the nucleosides Correct Answer Guanine has a ketone. Thy mine has a methyl l. Deamination of cytosine makes uracil.
Base differences btw RNA and DNA Correct Answer Uracil is found in RNA; Thymine in DNA
Base pair bonds Correct Answer G-C bond (3 H-bonds) is stronger than A-T bond (2 H-bonds). Incr G-C content --< higher melting temperature.
AA's necessary for purine synthesis Correct Answer Glycine A separate G glutamine
Nucleoside Correct Answer Base + ribose
Nucleotide Correct Answer Base + ribose + phosphate; linked by 3'-5' phosphodiester bond.
Purines are made from...? Correct Answer IMP precursor (see bottom/right) 
Pyrimidines are made from...? Correct Answer Orotate precursor, with PRPP added later. Last updated: 3 years ago
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