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Psychopharmacy: Fluoxetine
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Fluoxetine is an antidepressant drug from the selective serotonin reuptake inhibitor (SSRI) class which is mainly used for depression. Besides fordepression, fluoxetine and other SSRI groups are also ... indicated for obsessive-compulsive disorder (OCD), panic disorder, premenstrual dysphoric disorder, and bulimia. 1 Since its discovery in 1988, fluoxetine has become the most widely prescribed antidepressant drug due to its ease of use ( once a day), the risk of overdose is minimal, relatively tolerable, inexpensive, and a broad spectrum of indications. SSRI class drugs work by inhibiting the serotonin reuptake process through inhibition of the serotonin transporter (SERT). Since the pathogenesis of depression is thought to result from decreased levels of serotonin in the synaptic cleft, it is inhibition of SERT that is responsible for the antidepressant effect of fluoxetine [Show More]
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