NURSING NURSE-UN24 | Patho Exam 4 Questions & Answers-Define renal failure - 75% of the nephron total mass is gone How many nephrons are in each kidney? - Close to 1 million per kidney What is... the "All Nephrons Diseased" hypothesis? - When some kind of insult happens to the kidney, all nephrons are injured to some degree b/c they are vulnerable and delicate. What is the "Intact Nephron" hypothesis? - Nephrons are vulnerable, however; when something happens to a nephron it is all or nothing - it is either destroyed or unaffected and intact. How does the kidney respond to an insult of nephrons? - We sometimes find that intact nephrons hypertrophy to help take up the slack. What common condition is seen when we lose too many nephrons? - Uremia What is Uremia? - Retention of nitrogenous containing substances in the blood. What is our most severe symptom of renal failure? - Glomerulus filtration defecit Explain Glomerulus Filtration Rate (GFR) - GFR is the amount of plasma that is filtered through your glomerulus per minute. Your body should filter your entire blood volume through your kidneys every 20 minutes. What can also affect GFR? - Infections, inflammatory diseases, hyper/hypotension, SLE, diabetes and toxic substances What are causative organisms for UTI? - 80% E. coli 10% proteus 90% caused by gram negative rods What is the treatment for UTI? - Since 90% are caused by gram negative rods, we will not culture it, but prescribe an antibiotic which targets these organsisms. If UTI is recurring, we will culture it. What population is most likely to get a UTI and why? [Show More]
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