Anemia Iron Deficiency Anemia Pernicious/ Vit B-12
Deficiency Anemia Aplastic Anemia Sickle Cell Anemia
Patho:
-Reduction in oxygen transport in the blood
due to decreased hemoglobin
Patho:
-Insufficient
...
Anemia Iron Deficiency Anemia Pernicious/ Vit B-12
Deficiency Anemia Aplastic Anemia Sickle Cell Anemia
Patho:
-Reduction in oxygen transport in the blood
due to decreased hemoglobin
Patho:
-Insufficient iron
(necessary for synthesis of hemoglobin-carries O2) Patho:
-Vitamin B 12 deficiency
due to lack of intrinsic factor Patho:
-Impairment of failure of bone marrow
Pancytopenia
(decreased WBCs, RBCs, and platelets)
Patho:
-Formation of abnormal hemoglobin
Hemoglobin S (Hbs)
Causes:
-Depends in type Causes:
1. Diet – ex. Vegetarian
2. Chronic blood loss
3. Malabsorption
4. Liver disease
stores iron
Causes:
-Malabsorption
-Surgical resection Causes:
-idiopathic
-Myelotoxins Causes:
-Genetic:
-Recessive
- African & Middle Eastern decent
-Usually seen at 1 year old
Manifestation:
1. Fatigue*
2. Pallor*
3. Dyspnea*
4. Tachycardia* Manifestations:
* 1. Fatigue, pallor, dyspnea, tachycardia
2. Brittle hair
3. Spoon-shaped concave ridged nails
4. Stomatitis
5. Glossitis Manifestations:
*1. Fatigue, pallor, dyspnea, tachycardia
2. Paresthesia
3. Ataxia
4. Glossitis (also in iron anemia) Manifestations:
1. Infection
2. Anemia
3. Bleeding Manifestations:
*1. Fatigue, pallor, dyspnea, tachycardia
2. Jaundice
3. Splenomegaly
4.Pain Crisis: occlusion in blood vessel (triggered by smoking, dehydration, cold temp. infection, hypoxia)
Complications:
-Heart Failure Complications:
1. Sepsis
2. Hemorrhage Complications:
1. Acute chest syndrome
2. Infections
3.Stroke
4.Heart failure
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