Bio 101 NVCC Final Exam
Meiosis results in - ✔✔4 different haploid cells
The purpose of meiosis is to - ✔✔produce gametes (eggs and sperm)
There are _____ Cell divisions in meisosis - ✔✔2
Meiosis occurs in the ______
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Bio 101 NVCC Final Exam
Meiosis results in - ✔✔4 different haploid cells
The purpose of meiosis is to - ✔✔produce gametes (eggs and sperm)
There are _____ Cell divisions in meisosis - ✔✔2
Meiosis occurs in the _______ - ✔✔Ovary or testes
DNA replication occurs during ________ - ✔✔Interphase 1
Recombination or 'crossing over' occurs in ________ - ✔✔Prophase 1
Independent assortment of homologous chromosomes occurs in ________ - ✔✔Interphase 1
The DNA condenses, nuclear envelope disintegrates and centrioles move to opposite poles,
during ________ - ✔✔Prophase 1 and Prophase 2
The homologous chromosomes pair up during - ✔✔Prophase 1
Individual (single) chromosomes are arranged on the equator during ________ - ✔✔Metaphase
2
The sister chromatids seperate from each other during - ✔✔Anaphase 2
The homologous chromosomes separate from each other during ________ - ✔✔Anaphase 1
New nuclei form and the spindle fibers disintegrate during ________ - ✔✔Telophase 1 and 2
Oogenesis occurs in the ________ - ✔✔Ovaries
Spermatogenesis begins at ________ - ✔✔puberty
Oogenesis ends at ________ - ✔✔menopause
If fertilization occurs, the result of oogensis is - ✔✔1 egg, 2 polar bodies
Sperm are very large, mobile, and have a tail called a flagellum. True or False? - ✔✔True
Eggs are very large, immobile and don't have a tail. True or False? - ✔✔True
A woman can release (Ovulate) millions of eggs in her lifetime. True or False? - ✔✔False
Alleles are ________ - ✔✔alternate forms of a gene
Mendel counted up ________ in pea plants - ✔✔Phenotypes
Whether a trait is dominant or recessive is based on ________ - ✔✔The phenotype of the
heterozygote
A Genotype that is homozygous means ________ - ✔✔That each allele is the same, ie, AA, aa,
BB, bb.
When an individual has two different alleles, they are ________ - ✔✔Heterozygous
When an individual has two identical alleles, they are ________ - ✔✔Homozygous
The appearance of an individual is the ________ - ✔✔Phenotype
A test cross is set up to determine: - ✔✔The genotype of the dominant individual
If one allele masks (hides) the expression of the other allele, the masked allele is ________ -
✔✔Recessive
If a trait is equally as likely to be inherited by males as females, it is ________ - ✔✔autosomal
Albinism is an autosomal recessive trait. A man and a woman who are both wild type, have a
child with albinism. The genotype of the child can be: - ✔✔aa
Albinism is an autosomal recessive trait. A man and a woman who are both wild type, have a
child with albinism. The genotype of the mother is: - ✔✔Aa
Albinism is an autosomal recessive trait. A man and a woman who are both wild type, have a
child with albinism.
The probability that their next child is a carrier (heterozygous) is: - ✔✔2/4
Albinism is an autosomal recessive trait. A man and a woman who are both wild type, have a
child with albinism.
The probability that their next child has albinism is: - ✔✔1/4
Having freckles is an autosomal dominant trait. A man without freckles has a child with a
woman has freckles. The woman's mother does not have freckles.
The chance that they will have a child with freckles is: - ✔✔2/4
Having freckles is an autosomal dominant trait. A heterozygous couple who both have freckles,
have a _____ chance of having a child without freckles: - ✔✔1/4
Pedigrees show the pattern of inheritance of several genetic disorders within a family. True or
false? - ✔✔False
In pedigrees, squares represent females. True or false? - ✔✔False
If the phenotype of the heterozygote is intermediate between the homozygous parents, it is
probably an incomplete dominant trait.. True or false? - ✔✔True
A blood type A person can donate blood to someone who is blood type AB. True or false? -
✔✔True
Helicase: - ✔✔unwinds the DNA double helix
Ligase: - ✔✔joins DNA fragments together
RNA Primer - ✔✔RNA piece requuired to get DNA Polymerase started
This strand discontinuously builds new DNA - ✔✔Lagging
Anti-Parralel DNA strands - ✔✔One DNA strand runs 3' to 5' while the other runs 5' to 3'
Okasaki fragments - ✔✔short pieces of DNA on the lagging strand
DNA polymerase - ✔✔Adds/builds new DNA in a 5' to 3' direction
This strand continuously builds new DNA - ✔✔Leading
Semi-Converative replication is - ✔✔the new DNA double helix has one old strand and one new
strand
Complementary DNA base pairing for DNA Replication - ✔✔A-T, C-G
Give the complementary sequence of DNA on the opposite strand - and label the 5' and 3' end:
3' CATTAGAAGCTAAAGCGCTATAT 5' - ✔✔5' GTAATCTTCGATTTCGCGATATA 3'
Original DNA strand: 5 ' ATACAGATTAACCGG _________________________________
REPLICATION FORK moving to the right
Original DNA strand: 3' TATGTCTAATTGGCC ___________________________________
Fill in the leading and lagging strands and label the 5' and 3' ends: - ✔✔Original DNA strand: 5 '
ATACAGATTAACCGG _________________________________ REPLICATION FORK
moving to the right
3' TATGTCTAATTGGCC lagging strand ________________
5 ' ATACAGATTAACCGG leading strand ____________
Original DNA strand: 3' TATGTCTAATTGGCC ___________________________________
Sugar preset in DNA - ✔✔Deoxyribose
Type of sugar in RNA - ✔✔Ribose
Nitrogenous bases in DNA - ✔✔ACG&T
Nitrogenous bases in RNA - ✔✔ACG&U
Number of strands in DNA - ✔✔Two
Number of strands in RNA - ✔✔One
What is the promoter DNA sequence? - ✔✔DNA sequence that is bound by transcription factors
What is a Transcription factor? - ✔✔A Protein that binds the promoter region of DNA.
What is RNA Polymerase? - ✔✔Builds new RNA in a 5' to 3' direction
What is mRNA processing? - ✔✔It's a necessary function that prepares the pre-mRNA for
translation (occurs before translation).
What is the Coding DNA strand? - ✔✔The pre-mRNA is the same as this sequence, just in RNA
form.
What is the template DNA strand? - ✔✔The pre-mRNA is complementary to this sequence.
What is a poly-A tail? - ✔✔A tail added to the 3' end of mRNA that prevents it from being
degraded.
What is a G-Cap? - ✔✔A header added to the 5' end of the mRNA that allows it to exit from the
nucleus.
What is an Intron? - ✔✔Part of DNA sequence that are removed from the pre-mRNA
What is an Exon? - ✔✔It's part opf the DNA sequence that are kept in the mRNA.
transcribe this section of exon DNA on the Coding strand:
5' GCATGTTCAGGCTAAGCTACCTGTGAC 3' - ✔✔5'
GCAUGUUCAGGCUAAGCUACCUGUGAC 3'
List all blood types. - ✔✔A, B, AB, O
What is a pedigree? - ✔✔A chart that shows a single disorder within a family.
On a pedigree, what does a circle mean? - ✔✔Female.
On a pedigree, what does a square mean? - ✔✔Male.
What is complete/simple dominance? - ✔✔One characteristic is dominant over the opposing
one. So, white skin color could be dominant to darker skin color or vice versa.
What is incomplete dominance? - ✔✔Where both phenotypes are merged; ie, black cow and
white cow have a calf; the calf is grey.
Give the genotypes of all blood types. - ✔✔A- Ia Ia or Ia Io
B- Ib Ib or Ib Io
O- Io Io
When does hemolytic disease occur? - ✔✔When a woman is pregnant and their baby is Rh
negative.
Where and when does replication occur? - ✔✔S1 in Interphase
What does gene expression mean? - ✔✔That a gene is specific to tissue, so a liver tissue can't
function as a skin gene.
Where does Translation occur? What about transcription? - ✔✔Translation- Cytoplasm
Transcription- Nucleus
What is a codon? - ✔✔Set of three mRNA bases.
Give the instructions for translation. - ✔✔1.) Find the 5' end by locating the G-Cap.
2.) Search for 'Aug' start codon.
3.) Set reading prime codons.
4.) Continue, one codon at a time.
5.) Translation ends at a 'Stop' codon
6.) Amino acid chain disengages from mRna and folds into 3-D.
What is a simple tip for Translation? - ✔✔Keep all bases, only change T's to U's.
What is a Germ-line mutation? - ✔✔mutation that occurs in germ cells. Can be transmitted to
progeny and become a good or bad polymorphism in the gene pool.
What is a somatic mutation? - ✔✔One mutation that occurs in a body cell that is not passed on to
the offspring.
What are the two causes of mutation and what are their definitions? - ✔✔Indused: Mutagens
such as X-Rays, UV, smoking, etc.
Spontaneous: Caused by DNA replication that didn't perform well.
List types of mutations. Rank them in order of effect on protein products. - ✔✔Frame Shift:
Extremely bad, either done by an insertion mutation or deletion mutation. Either way, this moves
all codons by one in either direction.
Substitution: Not as bad, just changes a base.
Mutations can be positive or negative, give two examples of negative or positive mutations. -
✔✔Positive: Advanced hearing, advanced camouflage.
Negative: Blind or bright colored.
Name the two events in meiosis that contribute to gene reorganization - ✔✔Cross over/
recombination and Independent assortment.
What is the blood type that is the universal receiver, including ABO and Rh? - ✔✔AB pos
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