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PHARMACOLOGY 101 Clinical Pharmacology

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The nurse is administering an H-2 receptor antagonist to a patient with multiple burn trauma to prevent the development of stress ulcers based on the understanding that the drug: Correct response: provides protection of the stomach lining via acid blockage. Explanation: Histamine-2 receptor antagonists are used for stress ulcer prophylaxis because the drugs block the production of acid thereby protecting the stomach lining which is at risk because of decreased mucus production. Decreasing the acid being regurgitated into the esophagus explains the reason for use of the drug to treat erosive gastroesophageal reflux. Reducing the overall acid level explains the reason for use of the drug as short-term treatment of active duodenal ulcer. Blocking the overproduction of hydrochloric acid is the rationale for treatment of pathological hypersecretory conditions. A patient is prescribed misoprostol. The nurse would expect to administer this drug by which route? Correct response: Oral Explanation: Misoprostol is administered orally. The use of calcium carbonate is associated with the development of acid rebound. Correct response: True Which drug treats heartburn by neutralizing the acidity of the stomach by combining with hydrochloric acid (HCL) and increasing the pH of the stomach acid? Correct response: Magaldrate (Riopan) Explanation: Magaldrate (Riopan) is a combination product that contains magnesium and aluminate. Magaldrate (Riopan) treats heartburn by neutralizing the acidity of the stomach by combining with hydrochloric acid (HCL) and increasing the pH of the stomach acid. The nurse should warn a patient taking aluminum and calcium-containing antacids about which adverse effects? Correct response: Constipation Explanation: The nurse should warn a patient taking aluminum and calcium containing antacids about constipation that can be associated with taking products containing either medication. Which of the following herbal products have been used as a homeopathic remedy for GI problems, including motion sickness, nausea, vomiting, and digestion? (Choose one) Correct response: Ginger Explanation: Ginger is an herbal product that has been used as a homeopathic remedy for GI problems, including

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