NSG6005 Week 2 Quiz Bank Ch: 2, 5, 6, 10, 13
Chapter 2: Review of Basic Principles of Pharmacology
____ 1. A patient’s nutritional intake and lab work reflects hypoalbuminemia. This is critical to
prescribing because:
...
NSG6005 Week 2 Quiz Bank Ch: 2, 5, 6, 10, 13
Chapter 2: Review of Basic Principles of Pharmacology
____ 1. A patient’s nutritional intake and lab work reflects hypoalbuminemia. This is critical to
prescribing because:
A. Distribution of drugs to target tissue may be affected
____ 2. Drugs that have a significant first-pass effect:
C. Are rapidly metabolized by the liver and may have little if any desired action
____ 3. The route of excretion of a volatile drug will likely be:
B. The lungs
____ 4. Medroxyprogesterone (Depo Provera) is prescribed IM to create a storage reservoir of
the drug. Storage reservoirs:
C. Increase the length of time a drug is available and active
____ 5. The NP chooses to give cephalexin every 8 hours based on knowledge of the drug’s:
B. Biological half-life
____ 6. Azithromycin dosing requires the first day’s dose be twice those of the other 4 days of
the prescription. This is considered a loading dose. A loading dose:
A. Rapidly achieves drug levels in the therapeutic range
____ 7. The point in time on the drug concentration curve that indicates the first sign of a
therapeutic effect is the:
C. Onset of action
____ 8. Phenytoin requires a trough level be drawn. Peak and trough levels are done:
D. To determine if a drug is in the therapeutic range
____ 9. A laboratory result indicates the peak level for a drug is above the minimum toxic
concentration. This means that the:
B. Concentration will produce an adverse responseNSG6005 Week 2 Quiz Bank Ch: 2, 5, 6, 10, 13
____ 10. Drugs that are receptor agonists may demonstrate what property?
C. Desensitization or down-regulation with continuous use
____ 11. Drugs that are receptor antagonists, such as beta blockers, may cause:
B. An exaggerated response if abruptly discontinued
____ 12. Factors that affect gastric drug absorption include:
C. Lipid solubility of the drug
____ 13. Drugs administered via intravenous (IV) route:
B. Begin distribution into the body immediately
____ 14. When a medication is added to a regimen for a synergistic effect, the combined effect
of the drugs is:
B. Greater than the sum of the effects of each drug individually
____ 15. Which of the following statements about bioavailability is true?
A. Bioavailability issues are especially important for drugs with narrow therapeutic ranges or
sustained release mechanisms.
____ 16. Which of the following statements about the major distribution barriers (blood-brain or
fetal placental) is true?
B. The blood-brain barrier slows the entry of many drugs into and from brain cells.
____ 17. Drugs are metabolized mainly by the liver via Phase I or Phase II reactions. The
purpose of both of these types of reactions is to:
C. Change drug molecules to a form that an excretory organ can excrete
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