Why are nitrate-free periods every 24 hours necessary for the patient onnitroglycerin therapy?: To inhibit the development of tolerance 2. What does a low level of thyroid-stimulating hormone indicate?: Hyper-throidism 3
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Why are nitrate-free periods every 24 hours necessary for the patient onnitroglycerin therapy?: To inhibit the development of tolerance 2. What does a low level of thyroid-stimulating hormone indicate?: Hyper-throidism 3. What would be the best option to treat a newly diagnosed patient with a lowTSH level with?: Propanolol (Inderal) 4. Spironoaldactone (Aldactone) has what mechanism of action (MOA)?: Al-dosterone antagonist 5. Heparin exertsitstherapeutic action by what?: Upregulating the activity of oneof the body's natural anticoagulant molecules, antithrombin III 6. What physiologic action happens when the offending drug is administeredduring an anaphylactic reaction.: Mast cells liberate large doses of histamine. 7. What are two systemic psoriasis medications?: Photo-therapy and topicalcorticosteroids 8. What is the first choice of drug therapy for the majority of patients withuncomplicated stage I hypertension?: Thiazide diuretics 9. What is the effect of cardiac glycosides?: Digitalis glycosides have a negativechronotropic effect on the cardiac muscle cells. 10. Amenorrhea is the most common side effect of which birth control med-ication?: Medroxyprogesterone (Depo-Provera) 11. What is an anti-hypertensive agent which competes with epinephrine foravailable betareceptor sites?: Atenolol (Tenormin) 12. What type of action does nitrates have on the body?: Reduction in systemicvenous tone. 13. What is the recommended level of low-density lipoprotein cholesterol(LDL) for patients with known coronary artery disease?: 100mg/dl or less. 14. What is the MOA of group IV anti-dysrhythmia drugs?: Depressing phase 4depolarization and lengthening phases 1 and 2 repolarization. 15. Which drug therapy should be used to lower the serum concentration of thyroid hormones and re-establish eumetabolic state in a patient with Graves'disease?: Anti-thyroid drugs. 16. Which type of diuretic would be used for a stage I hypertension in a patientwith renal insufficiency?: Loop diuretic.
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