*NURSING > STUDY GUIDE > 566- Unit 3- Disorders of the Hip Exam Review 2024 A+ (All)
1. what happens to your cells with aging? 2. articular cartilage damage to OA 3. Your patient is a 52 yo male with a history that leads you to a primary hypothesis of L hip OA. However, during y... our exam you note that his L One is that our proteoglycan aggregation goes down. The size of the glycosaminoglycans complexes also goes down. Our proteoglycan synthesis is reduced, and those things combined lead to a reduction in the matrix structure of the articular cartilage and the decreased ability of that cartilage to attract fluid. Of course, fluid and then water is a lot of where the compressive and tensile stiffness of the cartilage comes from. So if we're attracting less fluid, we have less stiffness of the cartilage. If we get just more water in there and less healthy glycosaminoglycans complexes, the hydraulic pressure of that articular cartilage is going to also decrease. And what we end up with with aging is literally articular cartilage that is not as strong as the cartilage in younger folks. Therefore, slowly evolving articular disease that appears to originate in the articular cartilage is going to also affect the underlying bone and soft tissues-- this is osteoarthritis CONTINUES.... [Show More]
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