Pharmacology > EXAM > ADVANCED PHARMACOLOGY NR 565 MIDTERM CHAMBERLAIN 2024 COMPLETE STUDY QUESTIONS WITH VERIFIED ANSWERS (All)

ADVANCED PHARMACOLOGY NR 565 MIDTERM CHAMBERLAIN 2024 COMPLETE STUDY QUESTIONS WITH VERIFIED ANSWERS (GUARANTEED PASS) | RATED A+

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ADVANCED PHARMACOLOGY NR 565 MIDTERM CHAMBERLAIN 2024 COMPLETE STUDY QUESTIONS WITH VERIFIED ANSWERS (GUARANTEED PASS) | RATED A+ During what trimester is a pregnant woman most at risk for adverse drug reactions with potential long term consequences? - Answer>>> 1st trimester (fetus most at risk d/t rapid growth) What is BEERS criteria? - Answer>>> Recommendations of medications inappropriate for elderly (65 and older), prescriber ultimately decides What is the CYP450 (cytochrome P450) - Answer>>> liver enzyme system where medications are metabolized, can either be inducers or inhibitors and create drug-drug interactions CYP450 inducers - Answer>>> Speed up metabolism of drugs (drug is cleared faster), drug has lesser effect (decrease blood levels of drug), elevate CYP450 enzymes CYP450 inducers pneumonic - Answer>>> "Bullshit Crap GPS INDUCES rage" CYP450 inducer drug names - Answer>>> Barbituates, St John wort, Carbamazepine, rifampin, alcohol, phenytoin, griseofulvin, phenobarbital, sulfonylureas CYP450 inhibitors - Answer>>> inhibit metabolism, increase blood levels of medications CYP450 pneumonic - Answer>>> "VISA credit card debt INHIBITS spending on designers like CK to look GQ" CYP450 inhibitors drug names - Answer>>> Valproate, isoniazid, sulfonamides, amiodarone, chloramphenicol, ketoconazole, grapefruit juice, quinidine Physiological changes during pregnancy that impact pharmacodynamics and pharmacokinetic properties of drugs? - Answer>>> increase glomerular filtration rate leads to increase durg excretion increase hepatic metabolism decrease tone and motility of bowel increase drug absorption Examples of medications that can be teratogenic - Answer>>> Antiepileptic drugs, antimicrobials such as tetracyclines and fluoroquinolones, vitamin A in large doses, some anticoagulants, and hormonal medications such as diethylstilbestrol (DES). How is absorption of intramuscular medications different in neonates? - Answer>>> slow and erratic due to low blood flow in muscles first few days of life Why is absorption of medication in the stomach increased in infancy? - Answer>>> delayed gastric emptying Some medications that should be avoided in the pediatric patient? - Answer>>> glucocorticoids, discoloration of developing teeth with tetracyclines, and kernicterus with sulfonamides, levofloxacin (antibiotics) aspirin (Severe intoxication from acute overdose) what should be included in medication administration patient education? - Answer>>> dosage size and timing route and technique of administration duration of treatment drug storage nature and time course of desired responses nature and time course of adverse responses finish taking antibiotic

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