Pharmacology > EXAM PROCTORED > Advanced Pharmacology Maryville NURS 615- Exam V What assessments should be made before prescribing (All)
Why are ACE inhibitors the drug of choice in diabetic patients with hypertension? - ANS-ACE-Is will improve insulin sensitivity, as well as reduce the effects of DM on the kidneys. Protect the kidne... ys, watch for renal function, any creatinine >2.5 requires dose reduction. Prevents diabetic nephropathy or slow its progression. Reduce albuminuria and BP. ACEIs and ARBs should be used to treat the HTN. Renal protection, reduces the conversion of AT II and improve the insulin sensitivity. What is the drug of choice to improve symptoms for patients taking propranolol? - ANSIpratropium What is the most common adverse effect of an ACE inhibitor? - ANS-Dry, hacking cough in some patients. Can switch to an angiotensin blocker which won't cause cough. Reduce dose with either of these if Cr >2.5. Most are associated with hypotension, dizziness, HA, fatigue, orthostatic hypotension, tachyphylaxis. What is the action of an ACE inhibitor? - ANS-Decreases angiotensin II and aldosterone. Vasodilatation on the venous and arterial sides of the heart. Blocks the RAAS system leads to rennin acts on angiotensinogen to angiotensin I to angiotensin II through ACE. Angiotensin II stimulates aldosterone causing sodium and water while losing potassium via the kidney. ACE is also involved in the inactivation of bradykinin a vasodilator. Bradykin is what causes the cough (irritating the lungs). [Show More]
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