Chap 11
Fluid compartments
Intracellular 60%
Contained within the cell body About 25L
Veins, arteries, capillaries, heart, etc Extracellular 33%
Most important area of homeostasis, area outside of cells Divided into
...
Chap 11
Fluid compartments
Intracellular 60%
Contained within the cell body About 25L
Veins, arteries, capillaries, heart, etc Extracellular 33%
Most important area of homeostasis, area outside of cells Divided into intravascular space and interstitial space Extracellular fluid volume is about 15L
In-between the cells
Fluid Balance
Closely linked to/affected by electrolyte concentrations Fluid intake
2.3-3L a day Fluid loss
Minimum urine amount needed to excrete toxic waste products= 400-600
mL/day
Insensible water loss-through skin, lungs, stool. Usually 500 to 1L a day This increases during a fever, tachypnea and extreme stress
Facts to remember
Any fluid imbalances that occur=continuous assessment of UOP Urine output
Dehydrated pts, CHF, RF, Fluid volume deficient, and fluid volume overload IV fluids, diuretics
Daily weights
1L of water weighs 2.2lb, equal to 1kg
Weight change of 1lb= fluid volume change of about 500 mL Fluid volume deficit: Dehydration
Fluid intake/retention does not meet bodys fluid needs; results in fluid volume deficit Assessment
Thread and increased pulse rate; decreased BP; lethargy; decreased UOP; dry mucous membranes; constipation; thirst
Increased H&H (hemoconcentration), BUN, sodium, and urine specific gravity Causes-vomiting, diarrhea, ileostomy, laxatives, burns, fever, diuretics, GI
suctioning, and NPO
Interview/risk factors
Inquire about recent dietary habits Use of OTC diuretics
Outdoor activities
Weight gain and weight loss
Who at risk: hemorrhage, vomiting, diaherra, excessive sweating, NPO, sustained burn wounds, GI suction, Diuretics, uncontrolled diabetes, Poor intake
Flat neck and hand veins, increased RR, skin tenting, tongue wrinkles, dehydration, fever, UOP concentrated,
Urine specific gravity concentrated (the higher the dryer) BUN and Creatinine
BUN and Creatinine are kidney markers and are sensitive to decreased blood flow BUN (10-20) and Creatinine (06-1.2) rise when nitrogenous wastes are found in the
blood indicating kidney impairment
GFR (>65) typically has an inverse relationship (increased BUN and Creatinine with a decreased GFR)- chronic renal failure
Elevations can be caused by dehydration Fluid volume overload
Assessment
Bounding and increase pulse; elevated BP; dyspnea, crackles on lung auscultation; edema; decreased Hematocrit (hemodilution), decreased serum sodium and urine specific gravity (dilute urine). Weight gain is the best indicator
Causes- ESRD, CHF, water intoxication, SIADH, corticosteroid therapy, and rapid fluid replacement
Drug therapy
Diuretics (loop diuretics) Nutrition therapy
Fluid restriction ( 1200 ml/day) Salt restriction
Monitoring of intake and output Daily Weight!!!!
ESRD= End stage renal disease
SIADH= syndrome of inappropriate ADH
Edema- while standing ankles, feet, while laying down sacrum, back Extreme cases it will be everywhere
Electrolyte imbalances: etiology Hyponatremia
Due to sodium loss, water gain, or inadequate intake
Sodium loss: drugs; diuretics, anticonvulsants, SSRIs, antipsychotics, cancer meds Hypernatremia
Dehydration, excessive Na intake (sodium polystyrene, sodium bicarb, renal
issue)
Hypokalemia
Not enough in too much out, depleting drugs, medical conditions Not enough in: inadequate K intake
Too much out: GI fluid losses
Depleting drugs: diuretics, corticosteroids, insulin, excessive laxative use,
albuterol
Black licorice-acts like aldosterone
Hyperkalemia
Too much intake, blood products, drugs, not enough excreted, crush injury
supplements
Too much intake: increased dietary intake,, salt substitutes, potassium
Donated blood
Drugs: K sparing diuretics, ACE inhibitors, ARBs, NSAIDs Not enough excreted: renal failure ( low Na, K, protein diet) Crush injury: intracellular K released
Hypocalcemia
Inadequate intake, malabsorption, calcium loss, others Inadequate intake: calcium and vitamin D (sunlight)
Malabsorption: post menopausal women, diseases that affect the small bowel, drugs (anticonvulsants)
Calcium loss: loop diuretics
Others: renal failure, hypoparathyroidism, low magnesium, multiple blood transfusions, alkalosis, low albumin levels
Hypercalcemia
Increased resorption from the bone Hyperparathyroidism
Cancer
Thiazide diuretics Hypomagnesemia
Poor intake, poor GIT absorption, excessive GIT loss, excessive urinary losses Poor intake; alcoholics, patients on TPN or enteral feeding
Poor absorption: IBD, celiac disease
GIT loss: diarrhea, laxative use, NGT drainage Urinary loss: diuretics (loop and thiazide)
Hypermagnesemia
Excessive intake, impaired excretion
Excessive intake: magnesium containing antacids/laxatives Impaired excretion: renal dysfunction
Rare
Sodium imbalances: affect CNS Hyponatremia
Common: headache, irritability, disorientation/confusion, tired, abdominal cramping, muscle twitching/weakness, crave salt
Worst case scenario (critical low): psychosis, seizures, ataxia, airway issues Treatment
Mild: fluid restriction (safest), oral sodium supplements Critical: hypertonic 3% saline SLOWLY!!!
Nursing implications:
Monitor neurologic status, seizure/fall precautions, strict I/Os, implement fluid restriction, monitor labs
Hypernatremia
Common:
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