What is tyramine, where is it found (food sources), and why do we care? - Answer>>> --
tyramine acts as a catecholamine releasing agent (epinephrine, norepinephrine and dopamine)
--tyramine-rich foods: yeast, cheese, a
...
What is tyramine, where is it found (food sources), and why do we care? - Answer>>> --
tyramine acts as a catecholamine releasing agent (epinephrine, norepinephrine and dopamine)
--tyramine-rich foods: yeast, cheese, aged fish/meat, figs, bananas, wine
--pts. taking MAO-I's should avoid tyramine-rich foods because it can cause a HTN crisis
What is vincristine (Oncovin) used to treat? Action? - Answer>>> --prevents cell division in "M"
phase
--minimal myelosuppression, toxic to peripheral nerves
**assess for numbness, tingling in fingers and toes, constipation, difficulty walking (ataxia)
--FATAL is given via intrathecally (via spinal cord)
What are the adverse effects of protease inhibitors? And give a drug example - Answer>>> --
lopinavir/ritonavir (Kaletra)
--ADRS: hyperglycemia, fat redistribution, hyperlipidemia, reduced bone density,
hepatotoxicity, increased bleeding, prolonged QT interval, drug interactions (CYP p450)
What is the lab goal for patients with HIV? - Answer>>> --higher CD4 (<200= AIDS)
--lower viral load
What are the onset, peak, and duration of the long duration insulin? - Answer>>> (insulin
glargine, insulin detemir)
--onset= 60-120 min
--peak= 12-24 (NO peak in glargine)
--duration= 18-24 hrs
What are the taxane drugs? What are they used for? ADRs? - Answer>>> --paclitaxel (Taxol)
--docetaxal (Taxotere)
--used for lung, ovarian, gastric, breast
--infuse SLOWLY
--use H1 & H2 blockers BEFORE paclitaxel (Taxol) dose
--use dexamethasone BEFORE docetaxal (Taxotere)
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