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NUR2407 / NUR 2407 Exam 1 (Latest Update): Pharmacology - Rasmussen

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NUR 2407 Pharmacology Exam 1 Blood flow, pain, stress, solid foods, and pH affect what of oral medications? - Absorption Percentage of administered drug available for site of action Drug form,... route of administration, gastric mucosa and motility, administration with food and other drugs, and changes in liver metabolism all alter this - Bioavailability Protects the brain from foreign substances, highly lipid soluble drugs can cross, drugs with transport protein (free drugs) can also cross - Blood-Brain Barrier The time it takes for the amount of drug in the body to be reduced by half - Half-Life Occurs when the amount of drug being administered is the same as the amount of drug being eliminated, needed to achieve optimal therapeutic effect - Steady State A large initial dose given to reach therapeutic effect, while a steady state is being achieved with a maintenance dose, used for drugs with a long half-life - Loading Dose [Show More]

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