y
in Public Health Practice
Third Edition
An Introduction
to Applied Epidemiology and Biostatistics
October 2006
Updated May 2012
U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES
Centers for Disease Control and Preve
...
y
in Public Health Practice
Third Edition
An Introduction
to Applied Epidemiology and Biostatistics
October 2006
Updated May 2012
U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES
Centers for Disease Control and Prevention (CDC)
Office of Workforce and Career Development
Atlanta, GA 30333
Introduction
Page ii
CONTENTS
Acknowledgments................................................................................................................v
Introduction ...................................................................................................................... viii
Lesson One: Introduction to Epidemiology
Lesson Introduction ......................................................................................................... 1-1
Lesson Objectives ............................................................................................................ 1-1
Major Sections
Definition of Epidemiology ....................................................................................... 1-2
Historical Evolution of Epidemiology ....................................................................... 1-7
Uses .......................................................................................................................... 1-12
Core Epidemiologic Functions ................................................................................ 1-15
The Epidemiologic Approach .................................................................................. 1-21
Descriptive Epidemiology ....................................................................................... 1-31
Analytic Epidemiology ............................................................................................ 1-46
Concepts of Disease Occurrence ............................................................................. 1-52
Natural History and Spectrum of Disease ................................................................ 1-59
Chain of Infection .................................................................................................... 1-62
Epidemic Disease Occurrence ............................................................................
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