Question 1
1 out of 1 points
A patient has a blood serum drug level of 50 units/mL. The drug's halflife is 1 hour. If
concentrations above 25 units/mL are toxic and no more of the drug is given, how long will it
t
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Question 1
1 out of 1 points
A patient has a blood serum drug level of 50 units/mL. The drug's halflife is 1 hour. If
concentrations above 25 units/mL are toxic and no more of the drug is given, how long will it
take for the blood level to reach the nontoxic range?
Selected
Answer: A.
1 hour
Correct Answer:
A.
1 hour
Response
Feedback:
Halflife is the time required for the serum concentration of a drug to decrease
by 50%. After 1 hour, the serum concentration would be 25 units/mL (50/2).
After 2 hours the serum concentration would be 12.5 units/mL (25/2) and reach
the nontoxic range.
Question 2
1 out of 1 points
Talwin given in combination with Vistaril diminishes the adverse effects of nausea caused by
the Talwin. This drug interaction affecting the pharmacodynamics of the Talwin is
Selected Answer:
Correct Answer:
C.
an antagonistic effect.
Response
Feedback:
An antagonistic drug interaction results in a therapeutic effect that is less than the
effect of either drug alone because the second drug either diminishes or cancels
the effects of the first drug. An additive effect occurs when two or more “like”
drugs are combined and the result is the sum of the drugs' effects. A synergistic
effect occurs when two or more “unlike” drugs are used together to produce a
combined effect and the outcome is a drug effect greater than either drug's
activity alone. Potentiation is an interaction in which the effect of only one of the
two drugs is increased.
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