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QUIZ WEEK 1

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Question 1 1 out of 1 points A patient has a blood serum drug level of 50 units/mL. The drug's half­life is 1 hour. If concentrations above 25 units/mL are toxic and no more of the drug is given,... how long will it take for the blood level to reach the nontoxic range? Selected Answer: A. 1 hour Correct Answer: A. 1 hour Response Feedback: Half­life is the time required for the serum concentration of a drug to decrease by 50%. After 1 hour, the serum concentration would be 25 units/mL (50/2). After 2 hours the serum concentration would be 12.5 units/mL (25/2) and reach the nontoxic range.  Question 2 1 out of 1 points Talwin given in combination with Vistaril diminishes the adverse effects of nausea caused by the Talwin. This drug interaction affecting the pharmacodynamics of the Talwin is Selected Answer: Correct Answer: C. an antagonistic effect. Response Feedback: An antagonistic drug interaction results in a therapeutic effect that is less than the effect of either drug alone because the second drug either diminishes or cancels the effects of the first drug. An additive effect occurs when two or more “like” drugs are combined and the result is the sum of the drugs' effects. A synergistic effect occurs when two or more “unlike” drugs are used together to produce a combined effect and the outcome is a drug effect greater than either drug's activity alone. Potentiation is an interaction in which the effect of only one of the two drugs is increased. [Show More]

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