*NURSING > STUDY GUIDE > NR 507 Midterm Exam Study Guide. Latest (All)
NR 507 Midterm Exam Study Guide. Latest1. Concepts of anticholinergic drug and asthma: Anticholinergic drugs: block acetylcholine binding (primarily in the lungs) -promotes bronchiole dilation throug... h decrease in the parasympathetic response (tiotropium & ipratropium) is fast acting 2. Bronchitis & associated pathogenesis: Begins with an exposure to an irritant (tobacco smoke) – activates bronchiole smooth muscle constriction- mucus secretion- release of inflammatory mediators(histamine, prostaglandins & leukotrienes) normal response to occasional airborne site irritants- over bronchitis is over long term 3 months for over 2 consecutive years- = smooth muscle hypertrophy = increase bronchoconstriction, hypertrophy and hyperplasia of goblet cells= mucus hypersecretion, epithelia cell metaplasia = non-ciliated squamous cells, migration of more WBCs to site = inflammation and fibrosis in bronchial wall, thickening and rigidity of bronchial basement membrane= narrowing of bronchial passageways : [Show More]
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