NR508_Midterm
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NR508 Midterm Outline Chapter 1: The Role of the Advanced Practice Nurse as Prescriber Roles and responsibilities of APRN prescribers: Collaborate w/ physician on best drug to give patient, in dept... h knowledge of drugs, use pharma protocols, central role in educating nurses & patients on appropriate use of drugs Clinical judgement in Prescribing- Is a prescription the right tx? Goals of therapy, effective drugs for the disease? Monitoring goals met? Cost? Collaboration with other providers- different perspective on prescribing, critical for quality patient care Autonomy and Prescriptive authority- varies state to state. 21 states are independent prescribing, 26 are autonomous. Chapter 2: Review of Basic Principles of Pharmacology Metabolism: Biotransformation/ Chemical change of drug structure Enhance excretion, inactivate the drug, increase therapeutic action, activate pro-drug, increase/decrease toxicity Factors (Age, genetics, pregnancy, liver dz, time of day, environment, diet, alcohol, drug interactions) Drug Dose Determined: a) Dose-response relationship b) Therapeutic index: ratio of lethal dose/therapeutic dose c) Plasma level profile: Onset of action time d) Half-life e) Bioavailability: % of drug absorbed & available. Effected by incomplete absorption & first-pass metaboli [Show More]
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