Julia (aged 32) is BRCA1 positive, which is known to greatly increase
the risk for breast and ovarian cancer. She was tested because her
mother, who had ovarian cancer, was BRCA1 positive. Julia has
decided to have bo
...
Julia (aged 32) is BRCA1 positive, which is known to greatly increase
the risk for breast and ovarian cancer. She was tested because her
mother, who had ovarian cancer, was BRCA1 positive. Julia has
decided to have both of her ovaries removed because she believes
that, in her family, being BRCA1 positive increases the risk for
ovarian cancer only. How should a genetic counselor respond to
Julia’s statement?
Select one:
a. Accept Julia’s explanation as a manifestation of her autonomy
and remain nondirective in the interactions with her.
b. Discuss Julia’s responsibility to inform all the other female
members of her family about her BRCA1 status and cancer risk
c. Clarify that a BRCA1 mutation does not preferentially express
ovarian cancer over breast cancer in any given family.
d. Encourage her to consider a bilateral mastectomy.
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The correct answer is: Clarify that a BRCA1 mutation does not
preferentially express ovarian cancer over breast cancer in any
given family.
Question 2
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Which lethal cardiac arrhythmia can occur as a complication of long
QT syndrome?
Select one:
a. Mitral valve prolapse
b. Atrial node reentry tachycardia
c. Torsade de Pointes
d. Prolonged atrial fibrillation
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The correct answer is: Torsade de Pointes
Question 3
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What would be the patient’s response to a normal drug dose that
because of a genetic variation in an enzyme that prepares the drug
for elimination results in a blood drug level that is below the
minimum effective concentration (MEC)?
Select one:
a. The drug’s duration of action is longer than expected.
b. The risk for toxic side effects is increased.
c. Drug entry exceeds drug elimination
d. The intended response fails to be produced.
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The correct answer is: The intended response fails to be produced.
Question 4
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Which type of body tissue has the highest risk for cancer
development?
Select one:
a. Any tissue that retains the ability to divide
b. Bone tissue because its absorption of radiation is cumulative
c. Connective tissue that remains functional throughout life
d. Brain tissue because it does not respond well to injury
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