What are the basic mechanisms by which neuropharmocologic agents act?
o Can modify the disease process
o Act at the sites of actions which is the axons versus synapses and steps in synaptic transmission and effects of
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What are the basic mechanisms by which neuropharmocologic agents act?
o Can modify the disease process
o Act at the sites of actions which is the axons versus synapses and steps in synaptic transmission and effects of drugs on the steps of synaptic transmission
Transmittter synthesis is the first step in transmission. What are the other 4 steps?
o Transmitter storage, transmitter release, receptor binding, and termination of the transmission
• True or False: Neuropharmacologic drugs have high selectivity.
o True—the nervous system uses many different receptor types
• Information needed:
o Type of receptors—through which the drug acts
▪ Alpha and beta
o Normal responses to the activation of those receptors
▪ Agonists vs. antagonists
What the drug in questions does to the receptor function
What are the 3 functions of ANS?
o Regulates the heart
o Regulates the secretory glands, saliva glands, gastric, sweat, and bronchial
o It regulates smooth muscles: bronchi, blood vessels, urogenital system, and the GI tract
• What are the regulatory functions of the parasympathetic NS?
o Seven regulatory functions
▪ Slowing the heart rate
▪ Increasing the gastric secretions
▪ Emptying the bladder
▪ Emptying the bowel
▪ Focusing the eye for near vision,
▪ Constricting the pupil
▪ Contracting the bronchial smooth muscle
o It also regulates the digestion of food, excretion of waste, control of vision and conservation of energy
• What are the functions of the sympathetic NS?
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