What is physiological jaundice? - ✔✔-occurs when baby accumulates bilirubin
-secondary to immature liver in newborns
-Risk factor is prematurity
What level is conjugated hyperbilirubinemia? - ✔✔serum conjugated biliru
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What is physiological jaundice? - ✔✔-occurs when baby accumulates bilirubin
-secondary to immature liver in newborns
-Risk factor is prematurity
What level is conjugated hyperbilirubinemia? - ✔✔serum conjugated bilirubin concentration greater
than 1 mg/dL if the total bilirubin is less than 5.0 mg/dL or more than 20% of the total bilirubin if the the
total bilirubin is greater than 5 mg/dL (p. 862 AAP book)
What is breastfeeding jaundice? - ✔✔-due to poor intake that causes lack of stools and urine output
-common in first week and resolves once milk comes in and infant is feeding well-more stools and
urinary output
-peaks around 2-3 weeks
How do you diagnose jaundice? - ✔✔-dx with a bili level of 5 mg/dL
-12 mg/dL threshold for all newborns having jaundiced appearance
-direct/indirect bili levels
-CBC
-reticulocyte count
-use of bilitool.org
How do you treat jaundice? - ✔✔increased intake, longer feeding
indirect sunlight
phototherapy
IV fluids
Bili lights
BiliblanketWhat are other causes of jaundice? - ✔✔abnormal blood cell shapes (like sickle cell)
Rh incompatibility
cephalohematoma
polycythemia (increased RBCs, SGA infants, twins)
infection
specific enzyme disorders
What is biliary atresia? - ✔✔-life-threatening condition causing a blockage of bile ducts inside or outside
of liver
-leads to build-up of toxins (like bilirubin)
-malabsorption of fat-soluble vitamins A,D,E,K
-scaring of the liver, loss of tissue, cirrhosis
-not inherited
What are the two types of biliary atresia? - ✔✔fetal- noted in womb (other defects like heart, spleed,
intestines)
perinatal- appears 2-4 weeks after birth
What causes biliary atresia? - ✔✔-infection after birth (cytomegalovirus or rotavirus)
-autoimmune disorder
-developmental issue in womb
-exposure to toxic substances
What are symptoms of biliary atresia? - ✔✔jaundice
dark urine
light to white stools
poor wt gain and growth
How do you diagnose biliary atresia? - ✔✔any infant with jaundice present 2-3 weeks after birth-direct and indirect serum bilirubin
-LFTs
-abdominal x-ray
-abdominal US
-liver bx
How do you treat biliary atresia? - ✔✔-surgery (Kasai procedure), small intestine is attached directly to
the liver to allow bile to flow into the small intestine bypassing the cystic, hepatic, and common bile
duct.
-liver transplant
What are risk factors for dehydration? - ✔✔GI virus
NVD
What are s/sx of dehydration? - ✔✔-sunken fontanels
-tachycardia and decrease cap refill >2-3 seconds
-decrease urine output is sensitive but nonspecific
-increase in urine specific gravity
-decrease BP- late finding=more than 10% fluid loss
How do you treat dehydration? - ✔✔-if minimal, mild, moderate- oral rehydration
-if severe (drowsy, cold extremities, lethargic, sunken/dry eyes, very depressed anterior fontanel, no
tears, dry mouth/tongue, very decreased skin turgor, rapid/sometimes impalpable pulse,
decreased/unrecordable pulse, deep/rapid respiratory rate, markedly reduced urine output) - IV fluids
What is emesis? - ✔✔vomiting=symptom
must distinguish from regurgitation in infants
integrated response to noxious stimuli-coordinated by CNS
What is acute emesis?
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