What is Nagele's rule? - ✔✔due date = LMP + 9 months + seven days
What is developmental age? - ✔✔number of weeks and days since fertilization. typically used only in
research, as the exact date of fertilization is not
...
What is Nagele's rule? - ✔✔due date = LMP + 9 months + seven days
What is developmental age? - ✔✔number of weeks and days since fertilization. typically used only in
research, as the exact date of fertilization is not commonly known
What is gestational age? - ✔✔number of wks and days measured from the first day of the LMP.
How else can gestational age be determined? - ✔✔Fundal height: at 20wks, uterus is at the umbilicus
and grows approx 1 cm/wk
Quickening, or appreciation of fetal movt: typically occurs at 17-18 wks
Fetal heart tones: can be heard at 10-12 wks by Doppler
Ultrasound: measures fetal crown-rump length (CRL) at 5-12wks and measured biparietal diameter
(BPD), femur length (FL), and abd circumference (AC) from 13 wks. U/S measurement of GA is most
reliable during the first trimester
How does renal flow change in pregnancy? - ✔✔increases 25-50%
How does glomerular filtration rate change in pregnancy? - ✔✔increases early, then plateaus
How does uterine weight change in pregnancy? - ✔✔increases from about 60-70g to about 900-1200g
How does body weight change in pregnancy? - ✔✔average 11kg (25lb) increase
What is the standard for diagnosing pregnancy? - ✔✔B-hCG- produced by placenta; peaks at 100,000 mIU/mL by 10wks of gestation
- decreases throughout the second trimester; levels off in the third trimester
- hCG levels double approx every 48hrs during early pregnancy. This is often used to diagnose ectopic
pregnancy when doubling is abnormal
What is a quantitative B-hCG used for? - ✔✔- to diagnose and follow ectopic pregnancy
- to monitor trophoblastic disease
- to screen for fetal aneuploidy
What is a quad screen? - ✔✔1) Maternal serum alpha-fetoprotein
- produced by the fetus, crosses the placenta in small amounts and enters the maternal circulation
- Elevated: assoc w/ open neural tube defects (anencephaly, spina bifida), abd wall defects
(gastroschisis, omphalocele), multiple gestation, incorrect gestational dating, fetal death, and placental
abnormalities (e.g. placental abruption)
- Decreased: assoc w/ trisomy 21 and 18, fetal demise, and inaccurate gestational dating.
2) inhibin A
3) estriol
4) B-hCG
What quad screen results suggest Trisomy 18? - ✔✔ALL four decreased
What quad screen results suggest Trisomy 21 - ✔✔decreased AFP and estriol
Increased B-hCG and inhibin A
How does heart rate change in pregnancy? - ✔✔gradually increases 20%
How does blood pressure change in pregnancy? - ✔✔gradually decreases 10% by 34 wks, then increases
to prepregnancy values
How does stroke volume change in pregnancy? - ✔✔increases to maximum at 19wks, then plateausHow does cardiac output change in pregnancy? - ✔✔rises rapidly by 20%, then gradually increases an
additional 10% by 28wks
How does peripheral venous distention change in pregnancy? - ✔✔progressive increase to term
How does peripheral vascular resistance change in pregnancy? - ✔✔progressive decrease to term
How does respiratory rate change in pregnancy? - ✔✔unchanged
How does tidal volume change in pregnancy? - ✔✔increases by 30-40%
How does expiratory reserve change in pregnancy? - ✔✔gradual decrease
How does vital capacity change in pregnancy? - ✔✔unchanged
How does respiratory minute volume change in pregnancy? - ✔✔increases by 40%
How does blood volume change in pregnancy? - ✔✔increases by 50% in second trimester
How does hematocrit change in pregnancy? - ✔✔decreases slightly
How does fibrinogen change in pregnancy? - ✔✔increases
How do electrolytes change in pregnancy? - ✔✔unchanged
How does sphincter tone change in pregnancy? - ✔✔decreases
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