NURSING > STUDY GUIDE > NR 565 / NR565 Advanced Pharmacology Final Exam Study Guide| Rated A | Chamberlain College (All)

NR 565 / NR565 Advanced Pharmacology Final Exam Study Guide| Rated A | Chamberlain College

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Drug name Pharmacodynamics Pharmacotherapeutics Clinical use Drug interactions Adverse reactions Antacids, alum, ca, mag, sodium bicarb, bases Neutralize acids in GI tract, makes stomach acid more neutral Excreted in fece, mag, calcium, aluminim or sodium. Cannot be used with abd pain or fever. Hyperacidity, PUD, GERD, OTC, after meals and bedtime Seprate from other meds by two hours Diarrhea, constipation Antidiarrheals, pepto, loperamide, cholestyamine Kaolin and pectin hold onto bacteria, Lomotil is an opiod, binds to receptors to slow gastric motility, slows peristalsis. Toxic megacolon, bismuth not in children, use cautiously in older adults, metabolized by liver. iBS Diarrhea, hydration, electrolytes, opioids, travelers diarrhea Bismuth subsalicylate – toxicity with asa and hypoglycemia. Diphenoxylate with atropine – cns depressant Constipation, black tongue and gray stool, anticholigeric effects, CNS effects Cytoprotective Sucralfate’s minimal absorbed, misoprostol is rapidly absorbed Pregnant x, renal and feces Ulcers associated with NSAIDS Sucralfate, misoprosotol Constipation diarrhea Antiemetics Anticholinergic effects, block dopamine receptor with n/v Careful with EPS, seizure, not in children, n/v with drugs, motion sickness, antihistamines. CNS depression, anticholinergic effects, lithium toxicity and EPS with phenothiazines Drowsy, EPS, respeciallyiratory depression H2 receptor Inhibit acid secretion by parietal cells Caution in renal impairment, pregnant b, rantidiene and Pepcid ok in children, oral GERD, PUD, heartbutn Cimetidine uses several isoenzymes Impotence, hematological disorders, blood problems, confusion Prokinetics Stimulate motility of gi tract without stimulating gastric biliary or pancreatic secretions BBW tardive dyskensia, GI hemorrhage, depression, SI. GERD CNS depression, increase risk of EPS, anticholinergic effects Tardive dyskensia, dizziness, diarrhea, hypoglycemia Ppi Reduce h+ secretion by inhibiting the h+k+ atpase enzyme at secretor suface of cell Liver metabolism, pregnant b and c, children, short term usage Duodenal and gastric ulcers, GERD Interefere with absoption of drugs, increase INR with warafin, Plavix BBW Vitamin deficiencies, osteoporosis, cdif, pNA laxatives Stimulant: stimulate myenteric plexus Osmotic: draw water into lumen Bulk: natural Lubricant: soften stool Surfactant: reduce tension of stool Hyperosmolar: darws water into intestine Absorption differs, contraindicated with n/v, mag ox renal dysfunction Rapid respeciallyonse and short term, depends on class of drug Methylantexone with opioids Excessive bowel activity, cramp, flatulance

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