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NR 565 / NR565 Advanced Pharmacology Fundamentals Week 1 Quiz bank | Chapters 2, 7, 8 | LATEST, Q & A | Chamberlain College

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NR 565 / NR565 Advanced Pharmacology Fundamentals Week 1 Quiz bank | Chapters 2, 7, 8 | LATEST, Q & A | Chamberlain College Chapter 8. An Introduction to Pharmacogenomics ____ 1. Pharmacogenetic t... esting is required by the U.S. Food and Drug Administration prior to prescribing: 1. Erythromycin 2. Digoxin 3. Cetuximab 4. Rifampin ____ 2. Carbamazepine has a Black Box Warning recommending testing for the HLA-B*1502 allele in patients with Asian ancestry prior to starting therapy due to: 1. Decreased effectiveness of carbamazepine in treating seizures in Asian patients with the HLA-B*1502 allele 2. Increased risk for drug interactions in Asian patients with the HLA-B*1502 allele 3. Increased risk for Stevens-Johnson syndrome in Asian patients with HLA-B*1502 allele 4. Patients who have the HLA-B*1502 allele being more likely to have a resistance to carbamazepine ____ 3. A genetic variation in how the metabolite of the cancer drug irinotecan SN-38 is inactivated by the body may lead to: 1. Decreased effectiveness of irinotecan in the treatment of cancer 2. Increased adverse drug reactions, such as neutropenia 3. Delayed metabolism of the prodrug irinotecan into the active metabolite SN-38 4. Increased concerns for irinotecan being carcinogenic [Show More]

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