BIOS 390 ERIC KYLE Week 6 Exam Study Guide

BIOS 390 Week 6 Exam Study Guide/Assignment Question Set 1 (TCO 8) Which statement is not true about the nucleolus? (Select the correct answer.) (TCO 8) Ribosomes carry out the process of protein synthesis in th ...

BIOS 390 Week 6 Exam Study Guide/Assignment Question Set 1 (TCO 8) Which statement is not true about the nucleolus? (Select the correct answer.) (TCO 8) Ribosomes carry out the process of protein synthesis in the _____ after assembly in the _____ within a special compartment called the _____. (TCO 8) Which of the following is not a function of ribosome in protein synthesis? Question Set 2 (TCO 8) What is an anticodon? (TCO 8) Aminoacyl-tRNA synthetases are enzymes that (TCO 8) Transfer RNAs get charged with amino acids (where?) Question Set 3 (TCO 8) GTP hydrolysis is required for (Select the best answer.) (TCO 8) Hydrolysis of ATP indirectly fuels protein synthesis by (TCO 8) Protein synthesis is an anabolic process. Energy is provided by hydrolysis of Question Set 4 (TCO 8) Which is not a member of the eukaryotic ternary complex of translation initiation? (TCO 8) The start codon for translation in eukaryotes is (TCO 8) Initiation factors with helicase activity (eIF4G, eIF4E) associate with Question Set 5 (TCO 8) The stop codon is recognized by (TCO 8) Nascent polypeptides exit the ribosome via (TCO 8) The signal recognition particle (SRP) is a ribonucleoprotein complex that binds to ribosomes translating polypeptides that bear a signal sequence for targeting Question Set 6 (TCO 8) When the translation initiation factor eIF2 is phosphorylated in response to a sudden temperature increase or viral infection, translation can be greatly inhibited. In this case, phosphorylated eIF2 is under _____ control, and the phosphorylation of eIF2 leads to global (general or widespread) _____ control. (TCO 8) In response to unfavorable conditions, such as hypoxia or osmotic shock, translation can be globally repressed by (TCO 8) Phosphorylation of eIF2αblocks translation by Question Set 7 (TCO 8) Many steps in gene expression and cell signaling involve post-translational modification of proteins by (TCO 8) Which of the following is not true about molecular chaperones? (TCO 8) Allosteric regulation always involves Question Set 8 (TCO 8) You determine that a protein has an attached polyubiquitin chain. It is likely that this protein will be (TCO 8) Alzheimer’s disease, Huntington’s disease, and Creutzfeldt-Jakob disease are all examples of (TCO 8) A prion is an infectious protein Question Set 9 (TCO 9) When making a transgenic mouse by microinjection of foreign DNA into fertilized eggs, (TCO 9) When making transgenic mice, to determine whether there has been stable integration of a transgene into the mouse chromosome, tail biopsies are taken from the mouse pups and tested for the presence of the transgene by (TCO 9) When cloning an organism by nuclear transfer, Question Set 10 (TCO 9) Pharming is (TCO 9) Which of the following is not a suspected reason for the inefficiency/poor outcomes of reproductive cloning? (TCO 9) The term reprogramming refers to Question Set 11 (TCO 9) Plasmids are used as vectors in both plant and bacterial recombinant DNA technology. However, there is a major difference in the fate of genes introduced into bacteria on most bacterial plasmids and into plants on Ti plasmids. What is this difference? (TCO 9) Which is not a method by which one can introduce foreign DNA into a plant cell? (TCO 9) Find the incorrect statement. Question Set 12 (On your exam, one of the following 3 questions will be your short answer question.) (TCO 8) Mammalian ribosomes are composed of a 60S and a 40S subunit. What is S? (TCO 8) Discuss the roles of molecular chaperones in protein folding and degradation. (TCO 8) Describe possible fates for a misfolded protein in a cell.