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Week 3 notes: Depression: Twice as common in females as male MDD criteria 5 or more of the following symptoms 1. Depressed mood 2. Sleep Changes 3. Interest loss (anhedonia) 4. Guilt (worthless ... ness) 5. Energy loss 6. Concentration Reduction 7. Appetite Change 8. Psychomotor change 9. Suicide ideation/thoughts a. i.e. SIGECAPS b. Must last for 2 weeks or more c. Must not be caused by other condition i. Including substance use d. Treatments include i. Psychotherapy ii. Medications (SSRI, SNRI, MAOis, TCAs) iii. ECT for refractory (Electroconvulsive therapy) Mania – 3 or more of the following 1. Distractability 2. Irresponsibility/irritability/impulsiveness 3. Grandiose 4. Flight of Ideas 5. Activity increase 6. Sleep decrease 7. Talkative a. DIGFAST b. For at least 1 week for an episode c. Must cause significant impairment d. Not attributable to substances Hypomania – 3 or more of DIGFAST 1. For at least 4 days 2. No significant impairment – able to function Bipolar 1 - Requires 1 episode of mania, and may include episodes of depression and hypomania Bipolar 2 – Requires at least one episode of hypomania and an episode of major depression Treatment include mood stabilizers (lithium/valproate first line. Also lamotrigine, quetiapine, and atypical antipsychotics for acute mania) Cyclothymic disorder – alternates between hypomania and depression. Suffer some symptoms of DIGFAST, but not for 4 days. Also suffers criteria of SIGECAPS, but not enough to diagnose . 1. Symptoms present for 2 years or more 2. Treat with CBT and lithium, atypical antipsychotics Persistent depressive disorder (aka dysthymic d/o). 1. Decreased mood and SIGECAPS symptoms without meeting full MDD criteria for 2+ years; described as baseline sadness; still enjoy some things 2. Treat with CBT first and then SSRIs Adjustment disorder 1. Mood/anxiety symptoms < 3 months after a stressor, typically resolving within 6 months 2. Treat with supportive therapy and meds for symptoms (insomnia, nausea etc) Week 4 GAD 1. 5-10% lifetime prevalence. 2:1 women vs men 2. Definition: excessive worrying and anxiety for > 6 monhts a. Worry about school/grades, job, money, relationships, events, life b. Pathophys: Disrupted functional connectivity of the amygdala and its processing of fear and anxiety 3. Dx criteria: at least 3 of the following a. Restlessness b. Tires easily c. Problems concentrating d. Irritability e. Muscle tension f. Problems with sleep i. Symptoms must interfere with daily functionin... [Show More]

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