Preeclampsia dx? - ✔✔Bp > 140/90 AND proteinuria after 20 weeks gestation
Sign of severe preeclampsia? - ✔✔Epigastric pain, vision changes, hyperreflexia, Headache - indicates severe and convulsions are imminent
Tx
...
Preeclampsia dx? - ✔✔Bp > 140/90 AND proteinuria after 20 weeks gestation
Sign of severe preeclampsia? - ✔✔Epigastric pain, vision changes, hyperreflexia, Headache - indicates severe and convulsions are imminent
Txmtnet for severe preeclampsia? - ✔✔Hydralazine to control BP, magnesium, delivery asap
What is HELLP syndrome a form of? - ✔✔Preeclampsia
Treatment for CHF class 3 with LBBB and EF 25% on maximal therapy? - ✔✔Cardiac resynchronization therapy (gets both ventricles firing)
What dietary intervention can reduce the rate of sudden cardiac death? - ✔✔Omega 3
First line medications for descending aortic dissections? - ✔✔Beta blockers to lower HR and BP; nitroprusside can be given but not initially because it could cause reflex tachy
Txtment for SVT if adenosine fails? - ✔✔Beta blockers or non DHP ccb
Side effect of digoxin tox? - ✔✔Yellow vision
Best sodium blockers post MI? - ✔✔Lidocaine and Mexilitine (1B drugs) - Lido has Mexican tacos after MI
What can be used after adenosine, CCB and BB fail for SVT? - ✔✔Propafenone or flecainide (1C)
Txtment for HTN in blacks? - ✔✔Thiazide and CCB (diltiazem included)
What does still's murmur sound like? - ✔✔Systolic murmur sounding like guitar string thrumb
Indication for thrombolysis in MI? - ✔✔new onset LBBB
Warfarin should keep INR level at what after DVT? What about for mechanical valves? - ✔✔2-3; 2.5-3.5
Benefit of LWMH? - ✔✔Outpt txtment
Symptom of CHF in infant? - ✔✔Diaphoresis with feeding
Pressure gradient that warrants txtment of aortic stenosis? - ✔✔50 mmhg
What does sympatomatic aortic stensosi mean? - ✔✔Abysmal life expectancy
Is there a EF threshold for which you cant use beta blockers in HF? - ✔✔No
What is contraindication for using Beta blockers in HF? - ✔✔Symptomatic heart block (2nd or 3rd degree duh) or HR < 50 bpm
"Heart rate <50 beats per minute (bpm; unless a pacemaker is present).
If the patient has a heart rate <50 bpm and a pacemaker is present, proceed with beta blocker therapy and suggest CRT since the patient is likely to become pacemaker dependent."
https://www.uptodate.com/contents/use-of-beta-blockers-in-heart-failure-with-reduced-ejection-fraction?search=chf%20beta%20blocker&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1#H2593889026
Can mild asthma and COPD use beta blockers in HF? - ✔✔Yes, as long as theyre monitored
How to tell if worsening dyspnea if due to cardiac (eg hf) or pulmonary (eg COPD) etiology? - ✔✔BNP elevation (> 400 means 95% likely to be HF related)
Initial HF exacerbation txtment? - ✔✔Loop diuretic
What are BNP levels related to? - ✔✔Kidney function (kidneys excrete them, so might be higher in renal failure ... this is just understanding point, dont let it influence testing i think)
Is edema part of the criteria for preeclampsia? - ✔✔NO
When can periop beta blockers be considered? - ✔✔CAD with risk factors
In patients scheduled for noncardiac surgery, we do not start beta blockers to improve short-term outcomes. (See 'Patients without indications for long-term therapy' above.)
In patients scheduled for noncardiac surgery who have an indication for long-term beta blocker therapy but who have not yet had such therapy started, we individualize care, taking into account the benefits and risks associated with the preoperative initiation of therapy. (See 'Patients who may require preoperative initiation of therapy' above.)
In patients treated with long-term beta blockers for recommended indications, we suggest continuing beta blockade perioperatively (Grade 2B). (See 'Patients taking beta blockers' above.)
For those patients in whom beta blockers are continued, issues related to choice of agent, dose, and timing are discussed above. (See 'Patients taking beta blockers' above.)
https://www.uptodate.com/contents/management-of-cardiac-risk-for-noncardiac-surgery?search=perioperative%20beta%20blocker&source=search_result&selectedTitle=1~44&usage_type=default&display_rank=1#H362228968
Max target heart rate for elderly exercise program? - ✔✔60-75%
When is BNP secreted? - ✔✔Volume overload of ventricles
Drugs that reduce mortality in HF? - ✔✔BB, ACE/ARB, hydralazine with nitrate, spironolactone
Which drug should be avoided in HF? - ✔✔High dose ASA because it may cause renal fluid retention
Rate control for Afib? - ✔✔CCB or BB
Do pt with Afib on rhythm control still need anticoagulation? - ✔✔Yes
Contraindication for cilostazol? - ✔✔CHF
Cilostazol has proven benefit for the treatment of claudication with Food and Drug Administration (FDA) approval for treatment of symptomatic PAD, with a black box warning to avoid its use in patients with heart failure.
https://www.uptodate.com/contents/investigational-therapies-for-treating-symptoms-of-lower-extremity-peripheral-artery-disease?search=cilostazol&source=search_result&selectedTitle=2~35&usage_type=default&display_rank=1#H135435783
Drugs that reduce mortality after MI? - ✔✔BB and ACE
BP in severe preeclampsia? - ✔✔160/110 with proteinuria or > 140/90 with end organ sxs
Systolic blood pressure ≥160 mmHg or diastolic blood pressure ≥110 mmHg and proteinuria (with or without signs and symptoms of significant end-organ dysfunction).
Systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥90 mmHg (with or without proteinuria) and one or more of the following signs and symptoms of significant end-organ dysfunction:
•New-onset cerebral or visual disturbance, such as:
-Photopsia (flashes of light) and/or scotomata (dark areas or gaps in the visual field).
-Severe headache
-Altered mental status.
•Severe, persistent right upper quadrant or epigastric pain
•<100,000 platelets/microL.
renal dysfunction
•Pulmonary edema.
https://www.uptodate.com/contents/preeclampsia-clinical-features-and-diagnosis?search=severe%20preeclampsia&source=search_result&selectedTitle=2~90&usage_type=default&display_rank=2
DVT prophylaxis needed for hip and knee replacements? - ✔✔LMWH or warfarin
For initial VTE prophylaxis in patients undergoing total hip arthroplasty (THA) and total knee arthroplasty (TKA), in whom the risk of bleeding is low, our approach is the following (see 'Low bleeding risk: Pharmacologic prophylaxis (up to 10 to 14 days)' above):
•We recommend pharmacologic prophylaxis with or without intermittent pneumatic compression (IPC) devices rather than no prophylaxis (Grade 1B). While many experts combine mechanical and pharmacologic methods in high risk orthopedic patients, few studies have examined the benefits associated with this strategy.
•For most patients with THA and TKA we suggest low molecular weight (LMW) heparin or a direct oral anticoagulant (DOAC), rather than warfarin (Grade 2B). When a DOAC is selected, we prefer rivaroxaban or apixaban (rather than edoxaban or dabigatran) since experience is greater with these agents and evidence, on balance, suggests that, at minimum, they have equal efficacy with LMW heparin without any significant increase in the risk of bleeding.
https://www.uptodate.com/contents/prevention-of-venous-thromboembolism-in-adult-orthopedic-surgical-patients?search=hip%20replacement%20prophylaxis&source=search_result&selectedTitle=3~150&usage_type=default&display_rank=3#H9926118
Side effect of lithium? - ✔✔PTH elevation and hyperCa
Which DM drugs decrease gastric empyting? - ✔✔Amylin analogs and GLP-1 analogs and dpp4 inhibitors
What are the GLP-1 analogs? - ✔✔Exenatide and liraglutide
What are the amylin analogs? - ✔✔Pramlintide
Condition precluding metformin? - ✔✔Renal failure
What is a reason metformin is chosen over sulfonureas? - ✔✔weight loss - FA1
What is a MOA of metformin that sulfonurea doesn't have? - ✔✔Increases insulin sesntivity
How much is given for the 2 hr oral glucose tolerance test? - ✔✔75 g
What are the predm lab values? - ✔✔100-125 fasting or 140-199 2 hr
What does hypothyroidism do to bone age of peds pt? - ✔✔delays bone age relative to height and chronologic age
Complication of long term levothyroxine use? - ✔✔Osteoporosis
Indication for parathyroid secreting adenoma removal? - ✔✔< 50, calcium > 1 mg/dl above normal, decreased bone density, renal stone
What can angioedema also be called? - ✔✔Angioneurotic edema - contraindication
Which newborn jaundice is always pathologic? - ✔✔Direct bilirubinemia
When do you not use phototherapy for neonatal jaundice? - ✔✔Conjugated bilirubinemia
Midgut volvulus abd xray finding? - ✔✔Double bubble sign
Can abd xray be normal in midgut volvulus? - ✔✔Yes
Best way to dx midgut volvulus? - ✔✔Upper gi contrast study
How to tell pyloric stenosis from volvulus? - ✔✔NONbillous vomiting
Does the new rotavirus vaccine (rotateq) increase intussception risk? - ✔✔No -----however looking on uptodate it still is
Intussusception is a rare potential adverse effect of oral rotavirus vaccination in some settings; however, the risk of intussusception after rotavirus vaccination is much lower than the risk of severe rotavirus gastroenteritis in children who do not receive rotavirus vaccine.
https://www.uptodate.com/contents/rotavirus-vaccines-for-infants?search=rotateq&source=search_result&selectedTitle=2~45&usage_type=default&display_rank=1#H26
When is rotavirus vaccine given? - ✔✔2, 4, and 6 mo of age
What can hpylori eradication prevent? - ✔✔Nsaid induced ulcers (does not improve non ulcer dyspepsia, GERD, or prevent gastric cancer in asymptomatic pt)
Cause of infantile colic? - ✔✔Unknown
Is the BRAT diet effective for childhood diarrhea? - ✔✔No, give em a normal diet
When should hepB seroconversion be tested for in a child? - ✔✔9-12 mo
Water borne bugs that resist chlorine txted water? - ✔✔Cryptosporidium, giardia, hep A, Entamoeba histalytica
Cryptosporidium txtment? - ✔✔Nitazoxanide
Who should be routinely screened for hep C? - ✔✔IV drug users
Txtment if vaccinated nurse sticks herself with hep B pt? - ✔✔test nurses Ab titers (give IG and booster if low)
What is melanosis coli? - ✔✔Dark discoloration of the mucosa of the colon
What causes melanosis coli? - ✔✔Fecal stasis or bowel stimulants (like senna)
Red flag for irritable bowel syndrome? - ✔✔Night sxs
VTE prophylaxis in patient undergoing surgery with h/o VTE? - ✔✔subQ LMWH started 1-2 hrs prior to surgery and 1 day after
What are the three types of lesions in the mouth? - ✔✔Hairy nonscrapable leukoplakia caused by EBV, scrapable leukoplakia premalignant condition, and thrush
What is dry skin in the elderly called? - ✔✔Xerosis cutis
Finding in rosacea? - ✔✔Telangiectasias
Which worm that penetrates skin causes skin manifestations? - ✔✔Ancylostoma and necator
What does toxocara cause? - ✔✔Visceral involvement
Txtment for worms? - ✔✔Bendazoles - worms are bendy
What is infection of the nail folds called? - ✔✔Paronychia
Who gets paronychia? - ✔✔Workers who are exposed to chemical or wet periods
Txtment for paronychia? - ✔✔Avoid exposure and use strong topical steroids
First line txtment for eczema? - ✔✔Topical emollients and topical steroids
Txtment for leishmaniasis? - ✔✔Amphotericin B or sodium stibogluconate
What is the mask of pregnancy called? - ✔✔Melasma or cholasma
Txtment for scabies? - ✔✔Permethrin cream
What substance is visible on xrays? - ✔✔Glass
Most common cause of infection post axillary LN dissection? - ✔✔Non group A strep
15 month old with CAP PNA outpt txtment? - ✔✔High dose amox - card 122
when should solid foods be given to infants? - ✔✔4-6 mo
txtment for tibial stress fx? - ✔✔Air cast
test to order for older male complaining of low libido and beard growth aka late hypogonadism? - ✔✔Total test (Free test is too expensive)
first line txtment for plantar fasciitis? - ✔✔Heel inserts
complication of HSV-1 infection in child? - ✔✔Erythema multiforme
what determines difference between MGUS and multiple myeloma? - ✔✔Organ sxs in multiple myeloma
Cause of Femoral neuropathy? - ✔✔Diabetes
Common symptom in polymyalgia rheumatica? - ✔✔Fever
Most common electrolyte issue in a cachetic person when they start parenteral feeding? - ✔✔Hypophosphatemia (refeeding syndrome, not just in alcoholics)
How to correct hypocalcemia for hypoalbuminemia? - ✔✔Serum calcium plus .8 x 4 minus albumin
Management of hoarseness going on for 3 mo? - ✔✔Laryngiscopy
What cells does EBV infect? - ✔✔B cells on CD21
What lab finding is in EBV mono? - ✔✔Atypical lymphocytes (t cells)
Initial hyperCa management? - ✔✔IV fluids FIRST then bisphosphonates after theyre euvolemic
Which surgical fibroid treatment allows pregnancy in future? - ✔✔Myomectomy, not embolization
What increases the murmur in HCM? - ✔✔Valsalva because it decreases preload
Do PEG tubes improve quality of life for dementia pt? - ✔✔no
Initial test for COPD? - ✔✔Spirometry (PFTs)
What are PFTs also called? - ✔✔spirometry
What does pain with eye movement suggest? - ✔✔Orbital problem or can be seen with optic neuritis too
What is screening for colon cancer if first degree relative with cancer before 60? - ✔✔40 or 10 years before fam member and screen Q5 years
Side effect of hydralazine? - ✔✔Drug induced pleuritic - lupus
Antiarrhymic for wolf Parkinson white? - ✔✔Procainamide
What happens if you eat an extra 100 calories a day? - ✔✔Your weight will eventually stabilize and you'll stop gaining
Mild INTERMITTENT asthma txtment? - ✔✔Inhaled beta agonist
Mild PERSISTENT asthma txtment? - ✔✔Daily ICS plus beta agonist for sxs
Moderate persistent asthma txtment? - ✔✔Low dose ICS plus LABA, or moderate dose ICS
What medication do you need to stop before doing CT angiography? - ✔✔Metformin - wont be cleared and will build up causing lactic acidosis
Txtment for nursing home acquired PNA? - ✔✔Vanco, ceftazidime, levofloxacin
Which cephalosporins have pseudomonal coverage? - ✔✔Cefepime and ceftazidime cefoperazone
Txtment for nursing home acquired pna not requiring hospitalization? - ✔✔Anti pseudomonas cephalosporin (ceftazadime or cefepime)
plus
carbapenem or pip/tazo
plus
cipro/levo or aminoglycosides
plus
vanco for mrsa coverage
??
what skin/eye complications does pseudomonas causes? - ✔✔ecthyma gangrenosum - immunocomprimised
corneal ulcers/keratitis in contact wearers/minor eye trauma
Which SSRI is NOT safe in pregnancy? - ✔✔paroxetine
medication for osteoporosis if bisphosphonates fail? - ✔✔teriparitide
side effect of teriparitide? - ✔✔osteosarcoma
culture negative pyuria cause? - ✔✔chlamydia
what is apraxia? - ✔✔inability to perform an action
what kind of gait is seen in vision impairment? - ✔✔arms and legs abducted
what kind of gait is seen in frontotemporal dmentia? - ✔✔magnetic
when is "en bloc" turning seen and waht is it? - ✔✔vision impairment and parkinsons
multiple small steps to turn
are SSRIs good for anorexia? - ✔✔no
best anorexia txtment? - ✔✔family based therapy
When should oseltamivir phosphate be prescribed for flu? - ✔✔within 48 hours of onset of symptoms
is testing to confirm needed before oseltamivir can be given? - ✔✔no - clinical dx only and definitely not needed if someone has type 2 dm
medications used to prevent sxs in minor transfusion reactions? - ✔✔acetaminophen
benadryl
who should use aspirin to prevent CVD? - ✔✔45-79 where benefit outweighs risk of GI bleed
wrong - per usptf its 50-59 with 10% 10 year risk
The USPSTF recommends initiating low-dose aspirin use for the primary prevention of cardiovascular disease and colorectal cancer in adults aged 50 to 59 years who have a 10% or greater 10-year cardiovascular risk, are not at increased risk for bleeding, have a life expectancy of at least 10 years, and are willing to take low-dose aspirin daily for at least 10 years.
do you give iron or order ferritin level with a microcystic anemia? - ✔✔give iron first then check ferritin
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