: Fatty Acids
1. Which of the following fatty acids does not possess a double bond?
Proprionic
2. What type of reaction does lipase perform?
Hydrolysis
3. Upon exposure to glucagon, what is the phosphorylation state
...
: Fatty Acids
1. Which of the following fatty acids does not possess a double bond?
Proprionic
2. What type of reaction does lipase perform?
Hydrolysis
3. Upon exposure to glucagon, what is the phosphorylation state and activity of
Triacylglycerol Lipase?
Phosphorylated, active
4. Glycerol phosphate dehydrogenase performs what type of reaction?
Oxidation
5. In many CoA reactions, the energy for the reaction comes from the thioester bond of the
CoA. However, in charging CoA with a fatty acyl, what provides the energy?
Phosphoryl Transfer
6. The second step of B-oxidation, performs what type of chemical reaction?
Hydration
7. Consider a fatty acyl of 16 carbons that is attached to CoA. The carbon bonded to CoA
is radioactively labelled. How many cycles of B-oxidation must occur before a radio
labeled acetyl CoA appears?
1
8. Which of the following enzymes will provide NADPH for palmitate synthesis?
Malic Enzyme
9. What chemical change occurs to acetyl CoA in order to be converted to malonyl CoA?
Carboxylation
10. In a person with active fatty acid synthesis which of the following is likely true? (select all
that apply)
Hormone sensitive lipase active is decreased
Malic enzyme is elevated
Insulin is elevated
Quiz: Cholesterol and Phospholipids
1. An isomerization of isopentyl pyrophosphate results in what?
Dimethylallyl pyrophosphate
2. A newborn infant is born prematurely. The lecithin/ sphingomyelin ration is 1.3. What is
the likelihood this child will show respiratory distress syndrome?
75%
3. Since the basic structure of cholesterol has a phosphor-group the molecule is
amphipathic.
False
4. Which of the following is the primary product of the rate-limiting step of cholesterol
biosynthesis?
Mevalonate
5. Given the action of pyrophosphomevalonate decarboxylase, what might be one of the
products?
Carbon dioxide
6. Farnesyl pyrophosphate combines with what to form squalene?
Farnesyl pyrophosphate
7. Which of the following is used to regulate the rate-limiting enzyme of cholesterol
biosynthesis? (select all that apply)
Rate of translation
Half life of the enzyme
Rate of transcription
Phosphorylation status
Feedback inhibition
8. Converting 7-dehydrocholesterol to vitamin D3 requires the enzyme Dehydrocholesterol
Lyase.
False
9. What is the primary building block of cholesterol biosynthesis?
Isopentenyl Pyrophosphate
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