Pharmacology > STUDY GUIDE > NR565 Advanced Pharmacology Fundamentals - Terms Questions with Correct Answers and Definitions (All)
NR565 Advanced Pharmacology Fundamentals - Terms Questions with Correct Answers and Definitions
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NR565 Advanced Pharmacology Fundamentals Pharmacokinetics - ANS-The process by which drugs are absorbed, distributed within the body, metabolized, and excreted. Pharmacodynamics - ANS-The study of... what the drug does to the body Factors Affecting Drug Absorption - ANS-Rate of dissolution Surface area Blood flow Lipid solubility pH partitioning Factors Affecting Drug Distribution - ANS-Blood flow to tissues Ability to exit the vascular system Blood-brain barrier Protein-binding capacity Xenobiotics - ANS-substances that are foreign to the body, usually synthetic chemical compounds; medications are a common example Cytochrome P450 (CYP450) - ANS-xenobiotic-metabolizing enzymes necessary for the production of cholesterol and steroids and the detoxification of chemicals and drug metabolism. Function of Cytochrome P450 (CYP450) - ANS-responsible for phase 1 metabolism in which drugs are oxidized, reduced, or hydrolyzed [Show More]
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