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Student question Bank chapter 14: Textbook Clinical chemistry Principles, Techniques, and Correlations 7th edition

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Student question Bank chapter 14: Textbook Clinical chemistry Principles, Techniques, and Correlations 7th edition Which of the following hormones promotes gluconeogenesis? a. Growth hormone b. Hydrocortisone c. Insulin d. Thyroxine - ANS- b. Hydrocortisone Glucose oxidase oxidizes glucose to gluconic acid and a. H2O2 b. CO2 c. HCO3 d. H2O - ANS- H2O2 From glucose and ATP, hexokinase catalyzes the formation of a. Acetyl-CoA b. Fructose-6-phosphate c. Glucose-6-phosphate d. Lactose - ANS- c. Glucose-6-phosphate What is the preferred specimen for glucose analysis? a. EDTA plasma b. Fluoride oxalate plasma c. Heparinized plasma d. Serum - ANS- b. Fluoride oxalate plasma Hyperglycemic factor produced by the pancreas is a. Epinephrine b. Glucagon c. Insulin d. Growth hormone - ANS- b. Glucagon Polarographic methods of glucose assay are based on which principle? a. Nonenzymatic oxidation of glucose b. Rate of oxygen depletion measured c. Chemiluminescence caused by the formation of ATP d. Change in electrical potential as glucose is oxidized - ANS- b. Rate of oxygen depletion measured Select the enzyme that is most specific for β-D-glucose: a. Glucose oxidase b. Glucose-6-phosphate dehydrogenase c. Hexokinase d. Phosphohexose isomerase - ANS- a. Glucose oxidase Select the coupling enzyme used in the hexokinase method for glucose: a. Glucose dehydrogenase b. Glucose-6-phosphatase c. Glucose-6-phosphate dehydrogenase d. Peroxidase - ANS- a. Glucose dehydrogenase All of the following are characteristic of von Gierke disease EXCEPT a. Hypoglycemia b. Hypolipidemia c. Increased plasma lactate d. Subnormal response to epinephrine - ANS- b. Hypolipidemia The preferred screening test for diabetes in non- pregnant adults is measurement of a. Fasting plasma glucose b. Random plasma glucose c. Glycohemoglobin d. Depends on the patient factors - ANS- d. Depends on the patient factors Following the 2012 ADA guidelines, the times of measurement for plasma glucose levels during an OGTT in nonpregnant patients are a. Fasting, 1 hour, and 2 hours b. Fasting and 60 minutes c. 30, 60, 90, and 120 minutes d. Fasting, 30, 60, 90, and 120 minutes. - ANS- a. Fasting, 1 hour, and 2 hours Monitoring the levels of ketone bodies in the urine via nitroprusside reagents provides a semi-quanti- tative measure of a. Acetoacetate b. 3-β-Hydroxybutyrate c. Acetone d. All three ketone bodies - ANS- a. Acetoacetate A factor, other than average plasma glucose values, that can affect the HbA1c level is a. Serum ketone bodies level b. Red blood cell life span c. Ascorbic acid intake d. Increased triglyceride levels - ANS- b. Red blood cell life span Monitoring the levels of ketone bodies in the urine is a. Considered essential on a daily basis for all diabetic patients b. A reliable method of assessing long-term glycemic control c. Recommended for patients with type 1 diabetes on sick days d. Not recommended by the ADA - ANS- c. Recommended for patients with type 1 diabetes on sick days A urinalysis identifies a positive result for reducing sugars, yet the test for glucose (glucose oxidase reac- tion) was negative on the dipstick. What do these results suggest? CONTINUES....

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