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NR 508 Week 4 Midterm Possible Questions-Answers(Summer 2022)

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NR 508 Week 4 Midterm Exam; Possible Questions & Answers 1. Which of the following has been shown to prolong life in patients with chronic congestive failure in spite of having a negative inotropic effect on cardiac c ...

NR 508 Week 4 Midterm Exam; Possible Questions & Answers 1. Which of the following has been shown to prolong life in patients with chronic congestive failure in spite of having a negative inotropic effect on cardiac contractility? Carvedilol 2. Which of the following statements gives the best explanation for the use beta-blockers in congestive heart failure? Beta blockersreduce remodeling of the heart muscle by inhibiting mitogenic activity of catecholamine’s. 3. Which of the molecular mechanism of action of digoxin (Lanoxin, Cardoxin) used in the management of congestive heart failure? Inhibition of Na+/K+ATPase of the cell membrane 4. Which of the following is an aldosterone antagonist and is useful in the management of hypertensive patients with hypokalemia? (specific therapeutic application) Eplerenone 5. Which of the following agents is the most appropriate choice as a diuretic in patients with hypertension, heart failure and renal failure? (therapeutic multiple uses) Furosemide 6. Which is the atypical antidepressant known to block the reuptake of dopamine & norepinephrine (NDRI) and in known to treat depression & nicotine addiction? Bupropion (Wellbutrin / Zyban) 7. Which is the drug increase GABA activity & chloride conductance in neuronal cells thus inhibiting action potentials and is known to treat anxiety, convulsions and could cause marked sedation? Ativan-Lorazepam 8. Which of the following agents is a carbonic anhydrase inhibitor that works at the proximal convoluted tubule and is used in the treatment of ocular hypertension? Acetazolamide 9. Which class of drugs bind to 30s ribosome units and is used in the treatment of Proponibacterum ( acne), mycoplasma, chlamydae, and helicobacter infections? Tetracycline’ 10. The primary care NP see a patient several months after a myocardial infarction. The patient has been furosemide to treat heart failure.. The NP notes that the patient has edema of the hands , feet and ankles. The NP should add which drug? Chlorothiazide (Lozol) 11. MK is a 64-year-old male taking Lisinopril for HTN. One month afterstarting the drug he noted to have a decline in renal function. Which is true? Increased potassium levels c

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