CHM 371 Biochemistry of Metabolism Exam 1 2/19/14 In keeping with Creighton University’s ideals and with the Academic Integrity Code adopted by the College of Arts and Sciences, I pledge that this ... work is my own and that I have neither given nor received inappropriate assistance in preparing it. Name: Signature: No programmable calculators allowed Exam time: 50 minutes Part I. Multiple choice. Circle the letter of the best answer for each problem. (2 pts. each) 1. Which of the following is used during the first step of Edman degradation sequencing of a peptide? a) 1-fluoro-2,4-dinitrobenzene b) phenylisothiocyanate c) dicyclohexylcarbodiimide d) 9-fluorenylmethoxycarbonyl e) none of the above 2. One of the less common amino acids, hydroxyproline, is found with high frequency in collagen. Which of the following is the most likely mechanism by which hydroxyproline takes the place of proline in collagen? a) a tRNA specific for hydroxyproline b) posttranslational modification of proline c) a codon specific for hydroxyproline d) none of the above 3. The isoelectric point of a polypeptide is the pH at which a) all of the sidechains are ionized b) both the N- and C-termini are ionized c) the net charge on the peptide is zero d) pH 7.0 CONTINUED...... [Show More]
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