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Immunology Midterm Review| 50 questions| with complete solutions

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Bonds between Ag & Ab (covalent vs non-covalent) Correct Answer: non-covalent hapten Correct Answer: antigen is combined with carrier molecules in order to trigger immune response adjuvant Cor... rect Answer: Substance that increases the immune response to antigens What types of cells are directly involved in eradicating/killing/lysing the virally infected cells? Correct Answer: macrophages, neutrophils, dendritic cells T cells markers Correct Answer: CD4, CD8, CD25 B cells markers Correct Answer: proteins on cell surfaces used for differentiation. Ex.CD19, CR2, CD81 T cells co-receptors Correct Answer: CD4 and CD8 B cells co-receptors Correct Answer: binds signaling molecules in addition of primary receptor. ex. CD19, CR2, CD81 Co-stimulatory molecules (B, T & DC) Correct Answer: B7 (on b cell) binds to CD28 (on T cell) and DC cells bind to T cell via MHCII/Ag complex and TCR to promote T cell Ag presentation. B7 binds CD28 and CD40L (on t cell) binds CD40(on b cell) to activate B cell. Ig molecule Correct Answer: In NK cells, is the cytotoxic granules formation constitutive or inflammation-induced? Correct Answer: constitutive Antibody-dependent cellular cytotoxicity (ADCC) Correct Answer: IgG molecules attach to a cell targeting it for attack by a NK cell Fab vs Fc portions of an antibody Correct Answer: Fab portions are the two arms, Fc portion is the stem FC Receptors Correct Answer: FcyR: expressed on monocytes, machrophages and dendritic cells. binding of antibody by the Fc receptor leads to its uptake and destruction. FceR: expressed on basophils and mast cells. Primary vs secondary immune resp [Show More]

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