1. Why are nitrate-free periods every 24 hours necessary for the patient on nitroglycerin therapy?: To inhibit the development of tolerance
2. What does a low level of thyroid-stimulating hormone indicate?: Hyper- throi
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1. Why are nitrate-free periods every 24 hours necessary for the patient on nitroglycerin therapy?: To inhibit the development of tolerance
2. What does a low level of thyroid-stimulating hormone indicate?: Hyper- throidism
3. What would be the best option to treat a newly diagnosed patient with a low TSH level with?: Propanolol (Inderal)
4. Spironoaldactone (Aldactone) has what mechanism of action (MOA)?: Al- dosterone antagonist
5. Heparin exerts its therapeutic action by what?: Upregulating the activity of one of the body's natural anticoagulant molecules, antithrombin III
6. What physiologic action happens when the offending drug is administered during an anaphylactic reaction.: Mast cells liberate large doses of histamine.
7. What are two systemic psoriasis medications?: Photo-therapy and topical corticosteroids
8. What is the first choice of drug therapy for the majority of patients with uncomplicated stage I hypertension?: Thiazide diuretics
9. What is the effect of cardiac glycosides?: Digitalis glycosides have a negative chronotropic effect on the cardiac muscle cells.
10. Amenorrhea is the most common side effect of which birth control med- ication?: Medroxyprogesterone (Depo-Provera)
11. What is an anti-hypertensive agent which competes with epinephrine for available beta-receptor sites?: Atenolol (Tenormin)
12. What type of action does nitrates have on the body?: Reduction in systemic venous tone.
13. What is the recommended level of low-density lipoprotein cholesterol (LDL) for patients with known coronary artery disease?: 100mg/dl or less.
14. What is the MOA of group IV anti-dysrhythmia drugs?: Depressing phase 4 depolarization and lengthening phases 1 and 2 repolarization.
15. Which drug therapy should be used to lower the serum concentration of thyroid hormones and re-establish eumetabolic state in a patient with Graves' disease?: Anti-thyroid drugs.
16. Which type of diuretic would be used for a stage I hypertension in a patient with renal insufficiency?: Loop diuretic.
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