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1. A 16 year-old male has nodulocystic acne. What might have the greatest positive impact in managing his acne? Retin-A® plus minocycline Benzoyl peroxide plus erythromycin Isotretinoin (Accutane... ®) Oral antibiotics Isotretinoin (Accutane®) Explanation: Nodulocystic acne is the most severe form of acne vulgaris. Nodules and cysts characterize this disease. They can be palpated and usually seen on the skin, although, they actually are under the skin's surface. They develop when the follicle wall ruptures and leaks pus and cell contents in the dermis. The contaminated material infects adjoining follicles and the nodule develops. Isotretinoin is the only known effective treatment. 2. An infant is diagnosed with diaper dermatitis. Satellite lesions are visible. This should be treated with a: moisture barrier like zinc oxide. topical anti-fungal agent. topical anti-bacterial agent. low potency steroid cream. topical anti-fungal agent Explanation: The finding of satellite lesions associated with diaper dermatitis indicates a Candidal infection. This patient will be most effectively treated with a topical anti-fungal agent, allowing the lesions to be exposed to air for periods of time (like during a nap). A moisture barrier like zinc oxide is more beneficial when the diaper dermatitis is due to irritants like prolonged exposure to urine or feces. A low potency steroid cream should be used with caution in an infant with a fungal infection. A low potency cream in conjunction with an anti-fungal can be helpful if there is a great amount of underlying inflammation but has the potential to worsen the infection. [Show More]

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