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Clinical Pathophysiology Module 11 Endocrine

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Hypothyroidism a. Decreased metabolic rate b. Myxedema c. High serum cholesterol d. Both hyper and hypo can have goiter e. Manifestations i. Myxedema, mental sluggishness, somnolence, decreased ... cardiac output, Brady, constipation, decreased appetite,hyperventilation, cold interolerance, coarse dry skin and hair, weight gain f. Congenital Hypothyroidism- ***common cause of PREVENTABLE mental retardation** i. Appear normal at first, still benefiting from maternal hormones 2. Hyperthyroidism a. Increased metabolic rate, O2 consumption, use of metabolic fuels, and SNS responsiveness b. Manifestations i. thyroid storm, restlessness, wakefulness, increase cardiac output, Tachy, diarrhea, increased appetite, dyspnea, heat intolerance, sweating, thin and silky skin and hair, weight loss ii. Thyroid storm- very high fever, , extreme cardiovascular effects, severe CNS effects, high mortality rate 1. Can happen during stress, or from manipulation of hyperactive thyroid c. Graves Disease- autoimmune disease, abnormal stimulation of thyroid gland by thyroid stimulating [Show More]

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